Jisnuson Svasti, Professor

Email: jisnuson@cri.or.th

Office: Biomedical Science Building, 7th floor, Zone D

Phone: (66)2 553 8555 ext. 8561

Research Interests:

  • Cancer biomarkers
  • Genetic diseases


Selected Publications:

  1. Aspirin suppresses components of lymphangiogenesis and lymphatic vessel remodeling by inhibiting the NF-κB/VCAM-1 pathway in human lymphatic endothelial cells.
    Prangsaengtong O, Jantaree P, Lirdprapamongkol K, Ngiwsara L, Svasti J, Koizumi K
    Vasc Medp1358863X18760718(2018 Apr 1)
  2. Unravelling Pathophysiology of Crystalline Nephropathy in Ceftriaxone-Associated Acute Kidney Injury: A Cellular Proteomic Approach.
    Chatchen S, Pongsakul N, Srisomsap C, Chiangjong W, Hongeng S, Svasti J, Chutipongtanate S
    Nephronp(2018 Jan 16)
  3. p.X654R IDUA variant among Thai individuals with intermediate mucopolysaccharidosis type I and its residual activity as demonstrated in COS-7 cells.
    Ngiwsara L, Ketudat-Cairns JR, Sawangareetrakul P, Charoenwattanasatien R, Champattanachai V, Kuptanon C, Pangkanon S, Tim-Aroon T, Wattanasirichaigoon D, Svasti J
    Ann Hum Genet82p150-157(2018 May)
  4. Lupeol and stigmasterol suppress tumor angiogenesis and inhibit cholangiocarcinoma growth in mice via downregulation of tumor necrosis factor-α.
    Kangsamaksin T, Chaithongyot S, Wootthichairangsan C, Hanchaina R, Tangshewinsirikul C, Svasti J
    PLoS One12pe0189628(2017)
  5. The role of WT1 isoforms in vasculogenic mimicry and metastatic potential of human triple negative breast cancer cells.
    Bissanum R, Lirdprapamongkol K, Svasti J, Navakanitworakul R, Kanokwiroon K
    Biochem Biophys Res Commun494p256-262(2017 Dec 9)
  6. Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells.
    Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Keeratichamroen S, Ngiwsara L, Paricharttanakul NM, Lirdprapamongkol K, Weeraphan C, Svasti J, Srisomsap C
    Oncol Lett14p4361-4371(2017 Oct)
  7. Conference report: the 5th Asia Pacific Protein Association Conference joint meeting with the 12th International Symposium of the Protein Society of Thailand.
    Ketudat Cairns JR, Champattanachai V, Srisomsap C, Paricharttanakul NM, Verathamjamras C, Lirdprapamongkol K, Svasti J
    Biophys Rev9p857-860(2017 Dec)
  8. Molecular analysis of the novel <i>IDS</i> allele in a Thai family with mucopolysaccharidosis type II: The c.928C&gt;T (p.Gln310*) transcript is sensitive to nonsense-mediated mRNA decay.
    Ngiwsara L, Rojnueangnit K, Wattanasirichaigoon D, Tim-Aroon T, Sawangareetrakul P, Champattanachai V, Ketudat-Cairns JR, Svasti J
    Exp Ther Med13p2989-2996(2017 Jun)
  9. Secretomic profiling of cells from hollow fiber bioreactor reveals PSMA3 as a potential cholangiocarcinoma biomarker.
    Verathamjamras C, Weeraphan C, Chokchaichamnankit D, Watcharatanyatip K, Subhasitanont P, Diskul-Na-Ayudthaya P, Mingkwan K, Luevisadpaibul V, Chutipongtanate S, Champattanachai V, Svasti J, Srisomsap C
    Int J Oncol51p269-280(2017 Jul)
  10. Polymer-lipid-PEG hybrid nanoparticles as photosensitizer carrier for photodynamic therapy.
    Pramual S, Lirdprapamongkol K, Svasti J, Bergkvist M, Jouan-Hureaux V, Arnoux P, Frochot C, Barberi-Heyob M, Niamsiri N
    J Photochem Photobiol B173p12-22(2017 Aug)
  11. Molecular mechanism of cardol, isolated from Trigona incisa stingless bee propolis, induced apoptosis in the SW620 human colorectal cancer cell line.
    Kustiawan PM, Lirdprapamongkol K, Palaga T, Puthong S, Phuwapraisirisan P, Svasti J, Chanchao C
    BMC Pharmacol Toxicol18p32(2017 May 4)
  12. Involvement of vimentin in neurite outgrowth damage induced by fipronil in SH-SY5Y cells.
    Ruangjaroon T, Chokchaichamnankit D, Srisomsap C, Svasti J, Paricharttanakul NM
    Biochem Biophys Res Commun486p652-658(2017 May 6)
  13. Homodimers of Vanillin and Apocynin Decrease the Metastatic Potential of Human Cancer Cells by Inhibiting the FAK/PI3K/Akt Signaling Pathway.
    Jantaree P, Lirdprapamongkol K, Kaewsri W, Thongsornkleeb C, Choowongkomon K, Atjanasuppat K, Ruchirawat S, Svasti J
    J Agric Food Chem65p2299-2306(2017 Mar 22)
  14. Plasma prefractionation methods for proteomic analysis and perspectives in clinical applications.
    Chutipongtanate S, Chatchen S, Svasti J
    Proteomics Clin Appl11p(2017 Jul)
  15. Bridging the gap between clinicians and systems biologists: from network biology to translational biomedical research.
    Jinawath N, Bunbanjerdsuk S, Chayanupatkul M, Ngamphaiboon N, Asavapanumas N, Svasti J, Charoensawan V
    J Transl Med14p324(2016 Nov 22)
  16. Elevated O-GlcNAcylation of Extracellular Vesicle Proteins Derived from Metastatic Colorectal Cancer Cells.
    Chaiyawat P, Weeraphan C, Netsirisawan P, Chokchaichamnankit D, Srisomsap C, Svasti J, Champattanachai V
    Cancer Genomics Proteomics13p387-98(2016 09-10)
  17. Histopathological effect and stress response of mantle proteome following TBT exposure in the Hooded oyster Saccostrea cucullata.
    Khondee P, Srisomsap C, Chokchaichamnankit D, Svasti J, Simpson RJ, Kingtong S
    Environ Pollut218p855-862(2016 Nov)
  18. Penetration of Oxidized Carbon Nanospheres through Lipid Bilayer Membrane: Comparison to Graphene Oxide and Oxidized Carbon Nanotubes, and Effects of pH and Membrane Composition.
    Seemork J, Sansureerungsikul T, Sathornsantikun K, Sinthusake T, Shigyou K, Tree-Udom T, Jiangchareon B, Chiablaem K, Lirdprapamongkol K, Svasti J, Hamada T, Palaga T, Wanichwecharungruang S
    ACS Appl Mater Interfaces8p23549-57(2016 Sep 14)
  19. A Solanum torvum GH3 β-glucosidase expressed in Pichia pastoris catalyzes the hydrolysis of furostanol glycoside.
    Suthangkornkul R, Sriworanun P, Nakai H, Okuyama M, Svasti J, Kimura A, Senapin S, Arthan D
    Phytochemistry127p4-11(2016 Jul)
  20. A synthetic 2,3-diarylindole induces cell death via apoptosis and autophagy in A549 lung cancer cells.
    Rukkijakan T, Ngiwsara L, Lirdprapamongkol K, Svasti J, Phetrak N, Chuawong P
    Bioorg Med Chem Lett26p2119-23(2016 May 1)
  21. Unveiling a novel biomarker panel for diagnosis and classification of well-differentiated thyroid carcinomas.
    Paricharttanakul NM, Saharat K, Chokchaichamnankit D, Punyarit P, Srisomsap C, Svasti J
    Oncol Rep35p2286-96(2016 Apr)
  22. β-Elimination coupled with strong cation-exchange chromatography for phosphopeptide analysis.
    Buncherd H, Roseboom W, Chokchaichamnankit D, Sawangareetrakul P, Phongdara A, Srisomsap C, de Jong L, Svasti J
    Rapid Commun Mass Spectrom30p1695-1704(2016 Jul 30)
  23. Development and characterization of bio-derived polyhydroxyalkanoate nanoparticles as a delivery system for hydrophobic photodynamic therapy agents.
    Pramual S, Assavanig A, Bergkvist M, Batt CA, Sunintaboon P, Lirdprapamongkol K, Svasti J, Niamsiri N
    J Mater Sci Mater Med27p40(2016 Feb)
  24. Cardanol isolated from Thai Apis mellifera propolis induces cell cycle arrest and apoptosis of BT-474 breast cancer cells via p21 upregulation.
    Buahorm S, Puthong S, Palaga T, Lirdprapamongkol K, Phuwapraisirisan P, Svasti J, Chanchao C
    Daru23p55(2015 Dec 22)
  25. Non-adherent culture induces paclitaxel resistance in H460 lung cancer cells via ERK-mediated up-regulation of βIVa-tubulin.
    Atjanasuppat K, Lirdprapamongkol K, Jantaree P, Svasti J
    Biochem Biophys Res Commun466p493-8(2015 Oct 23)
  26. Analysis of Novel Mutations and Methylmalonyl-CoA Mutase Levels in Thai Patients with Isolated Methylmalonic Acidemia.
    Sawangareetrakul P, Ketudat Cairns JR, Vatanavicharn N, Liammongkolkul S, Wasant P, Svasti J, Champattanachai V
    Biochem Genetp(2015 Sep 14)
  27. Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells.
    Chaiyawat P, Chokchaichamnankit D, Lirdprapamongkol K, Srisomsap C, Svasti J, Champattanachai V
    Oncol Rep34p1933-42(2015 Oct)
  28. Proteomic Analysis Reveals Aberrant O-GlcNAcylation of Extracellular Proteins from Breast Cancer Cell Secretion.
    Netsirisawan P, Chokchaichamnankit D, Srisomsap C, Svasti J, Champattanachai V
    Cancer Genomics Proteomics12p201-209(2015 07-08)
  29. Aberrant O-GlcNAcylated Proteins: New Perspectives in Breast and Colorectal Cancer.
    Chaiyawat P, Netsirisawan P, Svasti J, Champattanachai V
    Front Endocrinol (Lausanne)5p193(2014)
  30. Comparative secretome analysis of cholangiocarcinoma cell line in three-dimensional culture.
    Tit-Oon P, Chokchaichamnankit D, Khongmanee A, Sawangareetrakul P, Svasti J, Srisomsap C
    Int J Oncol45p2108-16(2014 Nov)
  31. Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer.
    Phueaouan T, Chaiyawat P, Netsirisawan P, Chokchaichamnankit D, Punyarit P, Srisomsap C, Svasti J, Champattanachai V
    Oncol Rep30p2929-36(2013 Dec)
  32. Proteomic analysis reveals important role of 14-3-3σ in anoikis resistance of cholangiocarcinoma cells.
    Khongmanee A, Lirdprapamongkol K, Tit-oon P, Chokchaichamnankit D, Svasti J, Srisomsap C
    Proteomics13p3157-66(2013 Nov)
  33. Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer.
    Champattanachai V, Netsirisawan P, Chaiyawat P, Phueaouan T, Charoenwattanasatien R, Chokchaichamnankit D, Punyarit P, Srisomsap C, Svasti J
    Proteomics13p2088-99(2013 Jul)

Full list of publications