CGCB 502 Spectroscopic Methods for Organic Compounds and Biomolecules (3 credits)

Course Description

The combination of various spectroscopic techniques is essential in the structural elucidation of organic compounds, as well as in the kinetics and dynamics of some large biomolecules, such as proteins and nucleotides. Various techniques currently available and employed in modern spectroscopy will be discussed with the emphasis on nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS). The material includes topics in theoretical as well as practical aspects of modern NMR and MS techniques for structure elucidation of small organic compounds and for investigating various important properties of biomolecules. The principles of infrared (IR) spectroscopy and ultraviolet (UV) spectroscopy will also be highlighted. Additionally, the role of X-ray in the structure elucidation will be covered. The course is problem-solving oriented, and a number of problems related to structure elucidation ranging from simple to complex natural and synthetic compounds and kinetics/dynamics of biomolecules will be covered based on all spectral techniques.

Course Coordinator: Nopporn Thasana, Ph.D.