CGCB 503 Drug Discovery and Development (3 credits)

Course Description

The process of drug discovery and development encompasses different but intertwining fields of natural products chemistry, organic synthesis, combinatorial chemistry, biological screening, molecular modeling, and drug delivery. The course will introduce drugs from natural sources, as well as synthetic methodologies commonly employed in the synthesis of drugs and combinatorial chemistry to generate libraries of compounds, followed by biological screenings and high-throughput screening. The course will also explore various modern techniques in molecular modeling for determining ligand-receptor interactions to obtain structurally optimized lead compounds. Additionally, a range of methodologies commonly used to deliver the lead compound to its biological targets more effectively will be covered.

Course Coordinator: Montakarn Chittchang, Ph.D.