Jutatip Boonsombat, Ph.D.

jutatip.jpg

Affiliation: Laboratory of Natural Products (R603; Ext. 1608-9)
Office: R514B (Ext. 1504)
E-mail: jutatip@cri.or.th

Education

1999B.Sc. (Chemistry), 2nd Class HonorsChulalongkorn University, Thailand
2002M.Sc. (Organic Chemistry)Chulalongkorn University, Thailand
2008Ph.D. (Organic Chemistry)Emory University, USA

Research Interests

  • Developing efficient methodologies that can be applied toward the formation of heterocycles
  • Exploring synthetic approaches to construct biologically interesting compounds for medicinal chemistry development

Selected Publications

  1. Padwa A, Chughtai MJ, Boonsombat J, Rashatasakhon P. A Rh(II)-catalyzed Cycloaddition Approach towards the Synthesis of Komaroviquinone. Tetrahedron 2008; 64: 4758-4767.
  2. France S, Boonsombat J, Leverett CA, Padwa A. Cycloaddition across the Benzofuran Rings as an Approach to the Morphine Alkaloids. J. Org. Chem. 2008; 73: 8120-8123.
  3. Boonsombat J, Zhang H, Chughtai MJ, Hartung J, Padwa A. A General Synthetic Entry to the Pentacyclic Strychnos Alkaloid Family, using a [4 + 2] Cycloaddition/Rearrangement Cascade Sequence. J. Org. Chem. 2008; 73: 3539-3550.
  4. Padwa A, Chughtai MJ, Boonsombat J, Rashatasakhon P. A Rh(II)-Catalyzed Cycloaddition Approach toward the Synthesis of Komaroviquinone. Tetrahedron 2008; 64: 4758-4767.
  5. Bates RW, Boonsombat J, Lu Y, Nemeth JA, Sa-Ei K, Song P, Cai MP, Cranwell PB, Winbush S. N,O-Heterocycles as Synthetic Intermediates. Pure Appl. Chem. 2008; 80: 681-685.
  6. Padwa A, Boonsombat J, Rashatasakhon P. An Approach toward Oxidopyrylium Ylides using Rh(II)-Catalyzed Cyclization Chemistry. Tetrahedron Lett. 2007; 48: 5938-5941.
  7. Zhang H, Boonsombat J, Padwa A. Total Synthesis of (±)-Strychnine via a [4 + 2]-Cycloaddition/Rearrangement Cascade. Org. Lett. 2007; 9: 279-282.
  8. Padwa A, Boonsombat J, Rashatasakhon P, Willis J. Efficient Construction of the Oxatricyclo [6.3.1.00,0]dodecane Core of Komaroviquinone using a Cyclization/Cycloaddition Cascade of a Rhodium Carbenoid Intermediate. Org. Lett. 2005; 7: 3725-3727.
  9. Bates RW, Boonsombat J. Synthesis of (+)-Sedamine by Tethered Cyclofunctionalisation. Org. Biomol. Chem. 2005; 3: 520-523.
  10. Plemper RK, Erlandson KJ, Lakdawala AS, Sun A, Prussia A, Boonsombat J, Aki-Sener E, Yalcin I, Yildiz I, Temiz-Arpaci O, Tekiner B, Liotta DC, Snyder JP, Compans RW. A Target Site for Template-based Design of Measles Virus Entry Inhibitors. Proc. Natl. Acad. Sci. USA 2004; 101: 5628-5633.
  11. Bates RW, Boonsombat J. The Pyridinium Reduction Route to Alkaloids: A Synthesis of (±)-Tashiromine. J. Chem. Soc., Perkin Trans.1 2001; 7: 654-656.

Students Supervised

Thesis Advisees:

2010_sofia.jpg Ms. Sofia Bensulong, M.Sc. student (June 2010-present)