Professor Somsak Ruchirawat, Ph.D.

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Affiliation: Laboratory of Medicinal Chemistry
Office: R128/1 (Ext. 1503)
E-mail: somsak@cri.or.th

Education

1966B.Sc. (Chemistry), HonorsUniversity of Liverpool, UK
1969Ph.D. (Organic Chemistry)University of Liverpool, UK
1971-1972Postdoctoral TrainingMassachusetts Institute of Technology, USA

Research Interests

Organic chemistry, medicinal chemistry, organic synthesis, natural products chemistry

Selected Publications

  1. Ngokpol, S.; Suwakulsiri, W.; Sureram, S.; Lirdprapamongkol, K.; Aree, T.; Wiyakrutta, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Drimane sesquiterpene-conjugated amino acids from a marine isolate of the fungus Talaromyces minioluteus (Penicillium Minioluteum), Mar. Drugs 2015, 13, 3567-3580.
  2. Darsih, C.; Prachyawarakorn, V.; Wiyakrutta, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Cytotoxic metabolites from the endophytic fungus Penicillium chermesinum: Discovery of a cysteine-targeted michael acceptor as a pharmacophore for fragment-based drug discovery, bioconjugation and click reactions, RSC Adv. 2015, 5, 70595-70603.
  3. Tummatorn, J., Thongsornkleeb, C., Ruchirawat, S., Thongaram P., Kaewmee, B. Convenient and Direct Azidation of sec-Benzyl Alcohols by Trimethylsilyl Azide with Bismuth (III) Triflate Catalyst. Synthesis. 2015, 47, 323-329.
  4. Kaweetripob, W., Mahidol, C., Prawat, H., Ruchirawat, S. Cyclohexene long-chain fatty acid esters from Uvaria dulcis (Dunal) Phytochemistry Letters. 2015, 12, 248-251.
  5. Tummatorn, J., Poonsilp, P., Nimnual, P., Janprasit, J., Thongsornkleeb, C., Ruchirawat, S. Regioselective Synthesis of 3-Bromoquinoline Derivatives and Diastereoselective Synthesis of Tetrahydroquinolines via Acid-Promoted Rearrangement of Arylmethyl Azides. J. Org. Chem. 2015, 80, 4516-4525.
  6. Tangdenpaisal, K., Chuayboonsong, K., Sukjarean, P., Katesampao, V., Noiphrom, N., Ruchirawat, S., Ploypradith, P. Synthesis of C4-C5 Cycloalkyl-Fused and C6-Modified Chromans via ortho-Quinone Methides. Chem. Asian J. 2015, 10, 1050-1064.
  7. Tangdenpaisal, K.; Worayuthakarn, R.; Karnkla, S.; Ployprasith, P.; Intachote, P.; Sengsai, S.; Saimanee, B.; Ruchirawat, S.; Chittchang, M. Designing New Analogs for Streamlining the Structure of Cytotoxic Lamellarin Natural Products. Chem. Asian J. 2015, 10, 925-937.
  8. Pailee, P., Prachyawarakorn, V., Ruchirawat, S., Mahidol, C. Bioactive Cardinane Sesquiterpenes from the Stems of Alangium salviifolium. Chem. Asian J. 2015, 10, 910-914.
  9. Pingaew, R., Prachayasittikul, V., Mandi, P., Nantasenamat, C., Prachayasittikul, S., Ruchirawat, S., Prachayasittikul V. Synthesis and molecular docking of 1,2,3-triazole-based sulfonamides as aromatase inhibitors. Bioorg. Med. Chem. 2015, 23, 3472-3480.
  10. Panyadee, A., Sahakitpichan, P., Ruchirawat, S., Kanchanapoom, T. 5-Methyl ether flavone glucosides from the leaves of Bruguiera gymnrrhiza. Phytochemistry Letters. 2015, 11, 215-219.
  11. Ganihigama, D.U., Sureram, S., Sangher, S., Hongmanee, P., Aree, T., Mahidol, C., Ruchirawat, S.; Kittakoop, P. Antimycobacterial activity of natural products and synthetic agents: Pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolated of Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 2015, 89, 1-12.
  12. Pingaew, R., Mandi, P., Nantasenamat, C., Prachayasittikul, S., Ruchirawat, S., Prachayasittikul, V. Design, synthesis and molecular docking studies of novel N-Benzenesulfonyl-1,2,3,4-tetrahydroisoquinoline-based triazoles with potential anticancer activity. European Journal of Medicinal Chemistry. 2014, 81, 192-203.
  13. Prachayasittikul, V., Pingaew, R., Worachartcheewan, A., Nantasenamat, C., Prachayasittikul, S., Ruchirawat, S., Prachayasittikul, V. Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives. European Journal of Medicinal Chemistry. 2014, 84, 247-263.
  14. Pingaew, R., Saekee, A., Mandi, P., Nantasenamat, C., Prachayasittikul, S., Ruchirawat, S.; Prachayasittikul, V. Synthesis, biological evaluation and molecular docking of novel chalcone-coumarin hybrids as anticancer and antimalarial agents. European Journal of Medicinal Chemistry. 2014, 85, 65-76.
  15. Yongyat, C., Ruchirawat, S., and Boonyarattanakalin, S. “Controlled ring-opening polymerization of 1,2,6-tricyclic orthoesters of mannose toward size–controlled α-d-mannopyranan” e-Polymers, 2014, 14, 383–390.
  16. Hewage, R.T., Aree, T., Mahidol, C., Ruchirawat, S., Kittakoop, P. One strain-many compounds (OSMAC) method for production of polyketides, azaphilones, and an isochromanone using the endophytic fungus Dothideomycete sp., Phytochemistry 2014, 108, 87-94.
  17. Kittakoop, P., Mahidol, C., Ruchirawat, S. Alkaloids as Important Scaffolds in Therapeutic Drugs for the Treatments of Cancer, Tuberculosis, and Smoking Cessation. Current Topics in Medicinal Chemistry. 2014, 14, 239-252.
  18. Thorroad, S., Worawittayanont, P., Khunnawutmanotham, N., Chimnoi, N., Jumruksa, A., Ruchirawat, S., Thasana, N. Three new Lycopodium alkaloids from Huperzia carinata and Huperzia squarrosa. Tetrahedron. 2014, 70, 8017-8022.
  19. Tangdenpaisal, Kassrin., Ruchirawat, S., Ploypradith, P. Synthesis of the thyroid hormone analog GC-1 via Bi(OTf)3-catalyzed benzylation. Tetrahedron. 2014, 70, 6789-6795.
  20. Maibunkaew, T., Thongsornkleeb, C., Tummatorn, J., Bunrit, A., Ruchirawat, S. Practical and Metal-Free Electrophilic Aromatic Halogenation by Interhalogen Compounds Generated In Situ from N-Halosuccinimide and Catalytic TMSCI. Synlett. 2014, 25, 1769-1775.
  21. Tummatorn, J., Krajangsri, S., Norseeda, K., Thongsornkleeb, C., Ruchirawat, S. Anew synthetic approach to 6-unsubstitute phenanthridine and phenanthridine-like compounds under mild and metal-free conditions. Org.Biomol.Chem. 2014, 12, 5077-5081.
  22. Wibowo, M., Prachyawarakorn, V., Aree, T., Wiyakrutta, S., Mahidol, C., Ruchirawat, S., Kittakoop, P. Tricyclic and Spirobicyclic Norsesquiterpenes from the Endophytic Fungus Pseudolagarobasidium acaciicola. Eur. J. Org. Chem. 2014, 3976-3980.
  23. Dendup, T., Prachyawarakorn, V., Pansanit, A., Mahidol, C., Ruchirawat, S., Kittakoop, P. α-Glucosidase Inhibitory Activities of Isoflavanones, Isoflavones, and Pterocarpans from Mucuna pruriens. Planta Med. 2014, 80, 604-608.
  24. Wittayalai, S., Mahidol, C., Prachyawarakorn, V., Prawat, H., Ruchirawat, S. Terpenoids from the roots of Drypetes hoaensis and their cytotoxic. Phytochemistry. 2014, 99, 121-126.
  25. Worayuthakarn, R., Boonya-udtayan, Sasiwadee., Ruchirawat, S., Thasana, N. Total Synthesis of Unsymmetrical Benzils, Scandione and Calophione A. Eur. J. Org. Chem. 2014, 2496-2507.
  26. Tummatorn, J., M.P. Gleeson., Krajangsri, S., Thongsornkleeb, C., Ruchirawat, S. ZrCl4-promoted facile synthesis of indole derivatives. RSC.Adv. 2014, 4, 20048-20052.
  27. Sangsuwan, S., Sangher, S., Aree, Thammarat., Mahidol, C., Ruchirawat, S., Kittakoop, P. An organocatalyst from renewable materials for the synthesis of coumarins and chromenes: three-component reaction and multigram scale synthesis. RSC Adv. 2014, 4, 13708-13718.
  28. Kittakoop, P., Mahidol, C., Ruchirawat, S. Alkloids as Important Scaffolds in Therapeutic Drugs for the Treatments of Cancer, Tuberculosis, and Smoking Cessation. Current Topics in Medicinal Chemistry. 2014, 14, 239-252.
  29. Kaweetripob, W., Mahidol, C., Prawat, C., Ruchirawat, S. Lupane, Friedelane, oleanane, and ursane triterpenes from the stem of Siphonodon celastrineus Griff. Phytochemistry, 2013, 96, 404-417.
  30. Kumarn, S., Chimnoi, N., Ruchirawat, S. Synthesis of integerrimide A by an on-resin tandem Fmoc-deprotection-macrocyclisation approach. Org.Biomol.Chem. 2013, 11, 7760-7767.
  31. Sarnpitak, P., Trongchit, Kanokrat., Kostenko, Y., Sathalalai, S., Gleeson, M.P., Ruchirawat, S., Ploypradith, P. Syhthesis of Substituted 2-Arylindanes from E-(s-Stilbenyl)methanols via Lewis Acid-Mediated Cyclization and Nucleophililc Transfer from Trialkylsilyl Reagents. J.Org.Chem. 2013, 78, 8281-8296
  32. Nealmongkol, P., Tangdenpaisal, K., Sitthimonchai, S., Ruchirawat, S., Thasana, N. Cu(I)-Mediated lactone formation in subcritical water: a benign synthesis of benzopyranones and urolithins A-C. Tetrahedron. 2013, 9277-9283.
  33. Sahakitpichan, P., Mahidol, M., Disadee, W., Chimnoi, N., Ruchirawat, S., Kanchanapoom, T., Glucopyranosyloxybenzyl derivatives of (R)-2-benzylmalic acid and (R)-eucomic acid, and an aromatic glucoside from the pseudobulbs of Grammatophyllum speciosum. Tetrahedron, 2013, 69(3), 1031–1037.
  34. Tummatorn, J., Thongsornkleeb, C., Ruchirawat, S., Gettongsong, T., Synthesis of 2,4- unsubstituted quinoline-3-carboxylic acid ethyl esters from arylmethyl azides via a domino process. Org. Biomol. Chem., 2013,11(9), 1463-1467
  35. Boonyarattanakalin, S., Ruchirawat, S., Gleeson, M.P., Ring opening polymerization of mannosyl tricyclic orthoesters: rationalising the stereo and regioselectivity of glycosidic bond formation using quantum chemical calculations. Med. Chem. Commun., 2013,4(1), 265-268.
  36. Sureram, S.; Kesompun, C.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis. RSC Adv. 2013, 3, 1781-1788.
  37. Tangdenpaisal, K.; Phakhodee, W.; Ruchirawat, S.; Ploypradith, P. Facile synthesis of diarylmethanes via quinone methides. Tetrahedron. 2013, 69, 933-941.
  38. Phakeovilay, C., Disadee, W., Sahakitpichan, P., Sitthimonchai, S., Kittakoop, P., Ruchirawat, S., Kanchanapoom, T. Phenylethanoid and flavone glycosides from Ruellia tuberose L. Journal of Natural Medicines , 2013, 67, 228-233
  39. Thongsornkleeb, C., Rabten, W., Bunrit, A., Tummatorn, J., Ruchirawat, S. Facile access to 2,5-disubstituted-4-chloromethyl-3-iodofuran derivatives via ICI-mediated cyclization of 1-alkynylallylic alcohols. Tetrahedron Letters. 2012, 53, 6615-6619.
  40. Worachartcheewan, A., Prachayasittikul, S., Pingaew, R., Nantasenamat, C., Tantimongcolwat, T., Ruchirawat, S., Prachayasittikul, V. Antioxidant, cytotoxicity, and QSAR study of 1-adamantylthio derivatives of 3-picoline and phenylpyridines. Medicinal Chemistry Research , 2012, 3514-3522
  41. Boonya-udtayan, S., Eno, M., Ruchirawat, S., Mahidol, C., Thasana, N. Palladium-catalyzed intramolecular C–H amidation: synthesis and biological activities of indolobenzazocin-8-ones. Tetrahedron, 2012, 68(50), 10293–10301.
  42. S. Prachayasittikul, R. Pingaew, V. Yamkamon, A. Worachartcheewan, S. Wanwimolruk, S. Ruchirawat and V. Prachayasittikul, Chemical Constituents and Antioxidant Activity of Hydnophytum formicarum Jack. International Journal of Pharmacology, 2012, 8(5), 440-444.
  43. Siripong, P., Yahuafai, J., Piyaviriyakul, S., Kanokmedhakul, K., Koide, H., Ishii, T., Shimizu, K., Ruchirawat, S., Oku, N., Inhibitory Effect of Liposomal Rhinacanthin-N Isolated from Rhinacanthus nasutus on Pulmonary Metastasis in Mice. Biol. Pharm. Bull., 2012, 35(7), 1197-1200.
  44. Pingaew, R., Prachayasittikul, S., Ruchirawat, S., Prachayasittikul, V., Synthesis and cytotoxicity of novel 2,2′-bis- and 2,2′,2″-tris-indolylmethanes-based bengacarboline analogs. Archives of Pharmacal Research, 2012, 35(6), 949-954.
  45. Worayuthakarn, R., Nealmongkol, R., Ruchirawat, S., Thasana, N., Synthesis of benzoindoloquinolizines via a Cu(I)-mediated C–N bond formation. Tetrahedron, 2012, 68(13), 2864–2875.
  46. Senadeera, S., Wiyakrutta, S., Mahidol, C., Ruchirawat, S., Kittakoop, P A novel tricyclic polyketide and its biosynthetic precursor azaphilone derivatives from the endophytic fungus Dothideomycete sp. Org. Biomol. Chem., 2012, 10(35), 7220-7226.
  47. Pingaew, R., Prachayasittikul, S., Ruchirawat, S., Prachayasittikul, V. Synthesis and cytotoxicity of novel N-sulfonyl-1,2,3,4-tetrahydroisoquinoline thiosemicarbazone derivatives. Medicinal Chemistry Research , 2012, 22. 267-277
  48. Prawat, H.; Mahidol, C.; Kaweetripob, W.; Wittayalai, S.; Ruchirawat, S. Iodo-sesquiterpene hydroquinone and brominated indole alkaloids from the Thai sponge Smenospongia sp. Tetrahedron, 2012, 68, 6881-6886
  49. Prachayasittikul, S., Worachartcheewan, A., Pingaew, R., Suksrichavalit, T., Isarankura-Na-Ayudhya, C., Ruchirawat, S., Prachayasittikul, V. Metal complexes of uracil derivatives with cytotoxicity and superoxide scavenging activity. Letters in Drug Design and Discovery , 2012, 9 (3), pp. 282-287.
  50. Tummatorn, J.; Thongsornkleeb, C.; Ruchirawat, S. Acid-promoted rearrangement of arylmethyl azides: applications toward the synthesis of N-arylmethyl arenes and polycyclic heteroaromatic compounds. Tetrahedron. 2012, 68 (240, 4732-4739.
  51. Kaweetripob, W.; Mahidol, C.; Prachyawarakorn, V.; Prawat, H.; Ruchirawat, S. 5-Formylfurfuryl esters from Duabanga grandiflora. Phytochemistry. 2012, 76, 78-82.
  52. Disadee, W.; Mahidol, C.; Sahakitpichan, P.; Sitthimonchai, S.; Ruchirawat, S.; Kanchanapoom, T. Unprecedented furan-2-carbonyl C-glycosides and phenolic diglycosides from Scleropyrum pentandrum. Phytochemistry. 2012, 74, 115-122.
  53. Sureram, S.; Wiyakrutta, S.; Ngamrojanavanich, N.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Depsidones, Aromatase inhibitors and radical scavenging agents from the marine-derived fungus Aspergillus unguis CRI282-03, Planta Medica 2012, 78 6), 582-588.
  54. Pansanit, A.; Ingavat, N.; Aree, T.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Nitrone formation in phosphate buffer and aqueous solutions: novel chemistry inspired by a natural product, Tetrahedron Lett. 2012, 53 (16), 2129–2131.
  55. Sureram, S.; Senadeera, P. D. S.; Hongmanee, P.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis, Bioorg. Med. Chem. Lett. 2012, 22 (8), 2902-2905.
  56. Worawittayanon, P.; Ruadree, J.; Disadee, W.; Sahakitpichan, P. Sitthimonchai, S.; Thasana, N.; Ruchirawat, S.; Kanchanapoom, T. Iridoid and flavone glycosides from Asystasia salicifolia and their antioxidant activities. Biochemical Systematics and Ecology 2012, 40, 38-42.
  57. Wittayalai, S.; Sathalalai, S.; Thorroad, S.; Worawittayanon, P.; Ruchirawat, S.; Thasana, N. Lycophlegmariols A-D: Cytotoxic serratene triterpenoids from the club moss Lycopodium phlegmaria L. Phytochemistry 2012, 76, 117-123.
  58. Worayuthakarn, R.; Nealmongkol, P.; Ruchirawat, S.; Thasana, N. Synthesis of benzoindoloquinolizines via Cu(I)-mediated C-N bond formation. Tetrahedron 2012, 68 (13), 2864-2875.
  59. Worachartcheewan, A., Prachayasittikul, S., Pingaew, R., Nantasenamat, C., Tantimongcolwat, T., Ruchirawat, S., Prachayasittikul, V. Antioxidant, cytotoxicity, and QSAR study of 1-adamantylthio derivatives of 3-picoline and phenylpyridines. Medicinal Chemistry Research , 2011, pp. 1-9. Article in Press.
  60. Prachayasittikul, S., Worachartcheewan, A., Nantasenamat, C., Chinworrungsee, M., Sornsongkhram, N., Ruchirawat, S., Prachayasittikul, V. Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. European Journal of Medicinal Chemistry , 2011, 46 (2), pp. 738-742.
  61. Kanintronkul, Y., Worayuthakarn, R., Thasana, N., Winayanuwattikun, P., Pattanapanyasat, K., Surarit, R., Ruchirawat, S., Svasti, J. Overcoming multidrug resistance in human lung cancer with novel benzo[a]quinolizin-4-ones. Anticancer Research , 2011, 31 (3), pp. 921-927.
  62. Radomkit, S., Sarnpitak, P., Tummatorn, J., Batsomboon, P., Ruchirawat, S., Ploypradith, P. Pt(IV)-catalyzed generation and [4+2]-cycloaddition reactions of o-quinone methides. Tetrahedron, 2011, 67 (21), pp. 3904-3914.
  63. Panseeta, P., Lomchoey, K., Prabpai, S., Kongsaeree, P., Suksamrarn, A., Ruchirawat, S., Suksamrarn, S. Antiplasmodial and antimycobacterial cyclopeptide alkaloids from the root of Ziziphus mauritiana. Phytochemistry , 2011, 72 (9), pp. 909-915.
  64. Antia, B.S., Aree, T., Kasettrathat, C., Wiyakrutta, S., Ekpa, O.D., Ekpe, U.J., Mahidol, C., Ruchirawat, S., Kittakoop, P. Itaconic acid derivatives and diketopiperazine from the marine-derived fungus Aspergillus aculeatus CRI322-03. Phytochemistry , 2011, 72 (8), pp. 816-820.
  65. Prachyawarakorn, V., Mahidol, C., Ruchirawat, S. Longeracemosones. A-F, aromatase inhibitors from Dunbaria longeracemosa. European Journal of Organic Chemistry , 2011, (20-21), pp. 3803-3808.
  66. Pailee, P., Prachyawarakorn, V., Mahidol, C., Ruchirawat, S., Kittakoop, P. Protoberberine alkaloids and cancer chemopreventive properties of compounds from alangium salviifolium. European Journal of Organic Chemistry , 2011, (20-21), pp. 3809-3814.
  67. Ingavat, N., Mahidol, C., Ruchirawat, S., Kittakoop, P. Asperaculin A, a sesquiterpenoid from a marine-derived fungus, aspergillus aculeatus. Journal of Natural Products , 2011, 74 (7), pp. 1650-1652.
  68. Treeratanapiboon, L., Worachartcheewan, A., Suksrichavalit, T., Kiatfuengfoo, R., Prachayasittikul, S., Ruchirawat, S., Prachayasittikul, V. Bioactive 4-hydroxycinnamide and bioactivities of polyalthia cerasoides. EXCLI Journal , 2011, 10, pp. 16-22.
  69. Hutacharoen, P., Ruchirawat, S., Boonyarattanakalin, S. Biological activities of synthetic oligosaccharides and glycolipids from mycobacteria. Journal of Carbohydrate Chemistry , 2011, 30 (7-9), pp. 415-437.
  70. Sripha, K., Zlotos, D.P., Holzgrabe, U., Ruchirawat, S. A new synthetic approach to pentacyclic ring, 6,7,14,15-tetrahydro[1,5] diazocino[1,2-a:6,5-a']-8-dihydrodiindole. Heterocycles , 2011, 83 (11), pp.2627-2633.
  71. Bajgai, S.P., Prachyawarakorn, V., Mahidol, C., Ruchirawat, S., Kittakoop, P. Hybrid flavan-chalcones, aromatase and lipoxygenase inhibitors, from Desmos cochinchinensis. Phytochemistry, 2011, 72 (16), pp. 2062-2067.
  72. Disadee, W., Ploypradith, P., Aree, T., Chaichit, N., Ruchirawat, S. A novel approach for the synthesis of lophocladines A, B and C1 analogues. Tetrahedron Letters , 2011, 52 (46), pp. 6142-6144.
  73. Doungsoongnuen, S., Worachartcheewan, A., Pingaew, R., Suksrichavalit, T., Prachayasittikul, S., Ruchirawat, S., Prachayasittikul, V. Investigation on biological activities of anthranilic acid sulfonamide analogs. EXCLI Journal , 2011, 10, pp. 155-161.
  74. Sahakitpichan P., Disadee W., Ruchirawat S., Kanchanapoom T. 3-Hydroxydihydrobenzofuran Glucosides from Gnaphalium polycaulon. Chemical and Pharmaceutical Bulletin 2011, 59, 1160-1162.
  75. Prawat H., Mahidol C., Wittayalai S., Intachote P., Kanchanapoom T., Ruchirawat S. Nitrogenous sesquiterpenes from the thai marine sponge Halichondria sp. Tetrahedron 2011, 67 (31), 5651-5655.
  76. Disadee W., Mahidol C., Sahakitpichan P., Sitthimonchai S., Ruchirawat S., Kanchanapoom T. Flavonol 3-o-robinobiosides and 3-0-(2”-0-a-rhamnopyranosyl)-robinobuisudes from Sesuvium portulacastrum. Tetrahedron 2011, 67, 4221-4226.
  77. Bunrit A., Ruchirawat S., Thongsornkleeb C. A simple microwave-assisted preparation of 2-bromo-1-alkenes from 1-alkynes using the LiBr-TMSCI-TEAB reagent system. Tetrahedron Letter. 2011, 52 , 3124-3127
  78. Sahakitpichan P., Mahidol C., Disadee W., Ruchirawat S., Kanchanapoom T. Unusual glycosides of pyrrole alkaloid and 4’-hydroxyphenylethanamide from leaves of Moringa oleifera. Phytochemistry 2011, 72, 791-795.
  79. Tianpanic K., Prachya S., Wiyakrutta S., Mahidol C., Ruchirawat S., Kittakoop P. Radical Scavenging and Antioxidant Activities of Isocoumarins and a Phthalide Endophytic Fungus Colletotrichum sp. J.Nat.Prof. 2011, 74, 79-81.
  80. Gleeson MP, Deechongkit S, Ruchirawat S. Molecular Dynamics Investigation of Psalmopeotoxin I. Probing the Relationship between 3D Structure, Anti-malarial Activity and Thermal Stability. J. Mol. Model. 2011, 17(4):769-75.

Students Supervised

Co-advisees:

2008_anon.jpg Mr. Anon Boonrit, M.Sc. student (June 2008-August 2010)

2009_chakree.jpg Mr. Chakree Wattanasiri, Ph.D. student (June 2009-present)

2010_panatpong.jpg Mr. Panatpong Hutacharoen, M.Sc. student (June 2010-present)

2010_sofia.jpg Ms. Sofia Bensulong, M.Sc. student (June 2010-present)