Wannaporn Disadee, Ph.D.

wannaporn.jpg

Affiliation: Laboratory of Medicinal Chemistry (R603; Ext. 1609)
Office: R516C (Ext. 1510)
E-mail: wan\__1976@hotmail.com

Education

1999B.Sc. (Chemistry)Chulalongkorn University, Thailand
2003M.Sc. (Pharmaceutical Sciences in Medicinal Organic Chemistry)Chiba University, Japan
2006Ph.D. (Pharmaceutical Sciences in Medicinal Organic Chemistry)Chiba University, Japan

Research Interests

  • Development of methodologies for the synthesis of biologically active compounds and design new molecular structures for the study of medicinal chemistry
  • Development of new reagents for the asymmetric synthesis

Selected Publications

  1. Sahakitpichan P, Disadee W, Ruchirawat S, Kanchanapoom T. L-(-)-(N-trans-Cinnamoyl)-arginine, an Acylamino Acid from Glinus oppositifolius (L.) Aug. DC. Molecules 2010; 15: 6186-6192.
  2. Manaka T, Nagayama S-I, Disadee W, Yajima N, Kumamoto T, Watanabe T, Ishikawa T, Kawahata M, Yamaguchi K. Ring-opening Reactions of 3-Aryl-1-benzylaziridine-2-carboxylates and Application to the Asymmetric Synthesis of an Amphetamine-type Compound. Helv. Chim. Acta 2007; 90: 128-142.
  3. Disadee W, Ishikawa T, Kawahata M, Yamaguchi K. Guanidinium Ylide Mediated Aziridination: Identification of a Spiro Imidazolidine-oxazolidine Intermediate. J. Org. Chem. 2006; 71: 6600-6603.
  4. Disadee W, Ishikawa T. Chirality Transfer from Guanidinium Ylides to 3-Alkenyl (or 3-Alkynyl)aziridine-2-carboxylates and Application to the Syntheses of (2R,3S)-3-Hydroxyleucinate and D-Erythro-sphingosine. J. Org. Chem. 2005; 70: 9399-9406.
  5. Disadee W, Ishikawa T. Polymer-supported and Polymeric Chiral Guanidines: Preparation and Application to the Asymmetric Michael Reaction of Iminoacetate with Methyl Vinyl Ketone. Mol. Divers. 2005; 9: 321-331.
  6. Shikii K, Seki H, Yamaguchi K, Disadee W, Watanabe T, Ishikawa T. Facile Characterization of Polymer-supported Reagents using Cross Polarization Magic Angle Spinning Method in Solid State 13C-NMR. Chem. Pharm. Bull. 2004; 52: 864-865.
  7. Disadee W, Watanabe T, Ishikawa T. Polymer-supported DMI as a Potential Heterogeneous Dehydrating Agent: Application to Esterification and Amidation. Synlett 2003; 115-117.