Piyajit Watcharasit, Ph.D.

Email: piyajit@cri.or.th

Office: Biomedical Science Building, 4th floor, Zone A

Phone: (66)2 5538555 ext. 8274

Research Interest

Cell signaling, Apoptosis, Metabolic disease, Neurodegeneration

Selected Publications:

  1. Arsenic impairs insulin signaling in differentiated neuroblastoma SH-SY5Y cells.
    Niyomchan A, Visitnonthachai D, Suntararuks S, Ngamsiri P, Watcharasit P, Satayavivad J
    Neurotoxicology66p22-31(2018 Mar 8)
  2. Paraquat induces extrinsic pathway of apoptosis in A549 cells by induction of DR5 and repression of anti-apoptotic proteins, DDX3 and GSK3 expression.
    Hathaichoti S, Visitnonthachai D, Ngamsiri P, Niyomchan A, Tsogtbayar O, Wisessaowapak C, Watcharasit P, Satayavivad J
    Toxicol In Vitro42p123-129(2017 Aug)
  3. Chlorpyrifos promotes colorectal adenocarcinoma H508 cell growth through the activation of EGFR/ERK1/2 signaling pathway but not cholinergic pathway.
    Suriyo T, Tachachartvanich P, Visitnonthachai D, Watcharasit P, Satayavivad J
    Toxicology338p117-29(2015 Dec 2)
  4. Perfluorinated chemicals, PFOS and PFOA, enhance the estrogenic effects of 17β-estradiol in T47D human breast cancer cells.
    Sonthithai P, Suriyo T, Thiantanawat A, Watcharasit P, Ruchirawat M, Satayavivad J
    J Appl Toxicol36p790-801(2016 Jun)
  5. Insulin attenuates arsenic-induced neurite outgrowth impairments by activating the PI3K/Akt/SIRT1 signaling pathway.
    Niyomchan A, Watcharasit P, Visitnonthachai D, Homkajorn B, Thiantanawat A, Satayavivad J
    Toxicol Lett236p138-44(2015 Aug 5)
  6. Sodium arsenite inhibited genomic estrogen signaling but induced pERα (Ser118) via MAPK pathway in breast cancer cells.
    Nakareangrit W, Thiantanawat A, Visitnonthachai D, Watcharasit P, Satayavivad J
    Environ Toxicolp(2015 Mar 2)
  7. β-catenin involvement in arsenite-induced VEGF expression in neuroblastoma SH-SY5Y cells.
    Watcharasit P, Suntararuks S, Visitnonthachai D, Thiantanawat A, Satayavivad J
    Environ Toxicol29p672-8(2014 Jun)
  8. Estrogenic activities of sesame lignans and their metabolites on human breast cancer cells.
    Pianjing P, Thiantanawat A, Rangkadilok N, Watcharasit P, Mahidol C, Satayavivad J
    J Agric Food Chem59p212-21(2011 Jan 12)
  9. Acrylonitrile induced apoptosis via oxidative stress in neuroblastoma SH-SY5Y cell.
    Watcharasit P, Suntararuks S, Visitnonthachai D, Thiantanawat A, Satayavivad J
    J Appl Toxicol30p649-55(2010 Oct)
  10. GSK3 promotes arsenite-induced apoptosis via facilitation of mitochondria disruption.
    Watcharasit P, Thiantanawat A, Satayavivad J
    J Appl Toxicol28p466-74(2008 May)
  11. Attenuation of eNOS expression in cadmium-induced hypertensive rats.
    Yoopan N, Watcharasit P, Wongsawatkul O, Piyachaturawat P, Satayavivad J
    Toxicol Lett176p157-61(2008 Jan 30)
  12. Determination of levels of Mn, As, and other metals in water, sediment, and biota from Phayao Lake, Northern Thailand, and assessment of dietary exposure.
    Tupwongse V, Parkpian P, Watcharasit P, Satayavivad J
    J Environ Sci Health A Tox Hazard Subst Environ Eng42p1029-41(2007 Jul)
  13. Acrylonitrile-induced extracellular signal-regulated kinase (ERK) activation via protein kinase C (PKC) in SK-N-SH neuroblastoma cells.
    Chantara W, Watcharasit P, Thiantanawat A, Satayavivad J
    J Appl Toxicol26p517-23(2006 Nov-Dec)
  14. Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53.
    Watcharasit P, Bijur GN, Song L, Zhu J, Chen X, Jope RS
    J Biol Chem278p48872-9(2003 Dec 5)
  15. Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage.
    Watcharasit P, Bijur GN, Zmijewski JW, Song L, Zmijewska A, Chen X, Johnson GV, Jope RS
    Proc Natl Acad Sci U S A99p7951-5(2002 Jun 11)
  16. Microsample preparation by dielectrophoresis: isolation of malaria.
    Gascoyne P, Mahidol C, Ruchirawat M, Satayavivad J, Watcharasit P, Becker FF
    Lab Chip2p70-5(2002 May)