RESEARCH IN CHEMICAL BIOLOGY

Publications

2013

  1. Sarnpitak P, Trongchit K, Kostenko Y, Sathalalai S, Gleeson MP, Ruchirawat S, Ploypradith P. Synthesis of substituted 2-arylindanes from e -(2-stilbenyl)methanols via lewis acid-mediated cyclization and nucleophililc transfer from trialkylsilyl reagents. J. Org. Chem. 2013; 78: 8281-8296. Abstract
  2. Pingaew R, Worachartcheewan A, Nantasenamat C, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Synthesis, cytotoxicity and QSAR study of N-tosyl-1,2,3,4- tetrahydroisoquinoline derivatives. Arch. Pharmacal Res. 2013; 36: 1066-1077. Abstract
  3. Pingaew R, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Synthesis and structure-activity relationship of mono-indole-, bis-indole-, and tris-indole-based sulfonamides as potential anticancer agents. Molec. Divers. 2013; 17: 595-604. Abstract
  4. Pingaew R, Tongraung P, Worachartcheewan A, Nantasenamat C, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Cytotoxicity and QSAR study of (thio)ureas derived from phenylalkylamines and pyridylalkylamines. Med. Chem. Res. 2013: 22; 4016-4029. Abstract
  5. Lirdprapamongkol K, Sakurai H, Abdelhamed S, Yokoyama S, Athikomkulchai S, Viriyaroj A, Awale S, Ruchirawat S, Svasti J, Saiki I. Chrysin overcomes TRAIL resistance of cancer cells through Mcl-1 downregulation by inhibiting STAT3 phosphorylation. Int. J. Oncol. 2013; 43: 329-337. Abstract
  6. Athikomkulchai S, Awale S, Ruangrungsi N, Ruchirawat S, Kadota S. Chemical constituents of Thai propolis. Fitoterapia 2013; 88: 96-100. Abstract
  7. Srisung S, Suksrichavalit T, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Antimicrobial activity of 8-hydroxyquinoline and transition metal complexes. Int. J. Pharm. 2013; 9: 170-175. Abstract
  8. Prachayasittikul V, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. High therapeutic potential of Spilanthes acmella: A review. EXCLI J. 2013; 12: 291-312. Abstract
  9. Tummatorn J, Thongsornkleeb C, Ruchirawata S, Gettongsong T. Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters from arylmethyl azides via a domino process. Org. Biomol. Chem. 2013; 11: 1463-1467. Abstract
  10. Sureram S, Kesornpun C, Mahidol C, Ruchirawat S, Kittakoop P. Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus Aspergillus unguis. RSC Adv. 2013; 3: 1781-1788. Abstract
  11. Sahakitpichan P, Mahidol C, Disadee W, Chimnoi N, Ruchirawat S, Kanchanapoom T. Glucopyranosyloxybenzyl derivatives of (R)-2-benzylmalic acid and (R)-eucomic acid, and an aromatic glucoside from the pseudobulbs of Grammatophyllum speciosum. Tetrahedron 2013; 69: 1031-1037. Abstract
  12. Tangdenpaisal K, Phakhodee W, Ruchirawat S, Ploypradith P. Facile Synthesis of Diarylmethanes via Quinone Methides. Tetrahedron 2013; 69: 933–941. Abstract
  13. Boonyarattanakalin S, Ruchirawat S, Gleeson MP. Ring opening polymerization of mannosyl tricyclic orthoesters: rationalising the stereo and regioselectivity of glycosidic bond formation using quantum chemical calculations. Med. Chem. Commun. 2013; 4: 265-268. Abstract
  14. Phakeovilay C, Disadee W, Sahakitpichan P, Sitthimonchai S, Kittakoop P, Ruchirawat S, Kanchanapoom T. Phenylethanoid and Flavone Glycosides from Ruellia tuberosa L. J. Nat. Med. 2013; 67: 228-233. Abstract
  15. Pingaew R, Prachayasittikul S, Ruchirawat S, Prachayasittikul, V. Synthesis and cytotoxicity of novel N-sulfonyl-1,2,3,4-tetrahydroisoquinoline thiosemicarbazone derivatives. Med. Chem. Res. 2013; 22: 267-277. Abstract

2012

  1. Thongsornkleeb C, Rabten W, Bunrit A, Tummatorn J, Ruchirawat S. Facile Access to 2,5-Disubstituted-4-chloromethyl-3-iodofuran Derivatives via ICl-mediated Cyclization of 1-Alkyl-2-alkynylallylic Alcohols. Tetrahedron Lett. 2012; 53: 6615–6619. Abstract
  2. Senadeera SPD, Wiyakrutta S, Mahidol C, Ruchirawat S, Kittakoop P. A novel tricyclic polyketide and its biosynthetic precursor azaphilone derivatives from the endophytic fungus Dothideomycete sp. Org. Biomol. Chem. 2012; 10: 7220-7226. Abstract
  3. Pansanit A, Ingavat N, Aree T, Mahidol C, Ruchirawat S, Kittakoop P. Nitrone formation in phosphate buffer and aqueous solutions: novel chemistry inspired by a natural product. Tetrahedron Lett. 2012; 53: 2129–2131. Abstract
  4. Tummatorn J, Thongsornkleeb C, Ruchirawat S. Acid-promoted Rearrangement of Arylmethyl Azides: Applications toward the Synthesis of N-arylmethyl Arenes and Polycyclic Heteroaromatic Compounds. Tetrahedron 2012; 68: 4732-4739. Abstract
  5. Sureram S, Senadeera SP, Hongmanee P, Mahidol C, Ruchirawat S, Kittakoop P. Antimycobacterial Activity of Bisbenzylisoquinoline Alkaloids from Tiliacora triandra against Multidrug-resistant Isolates of Mycobacterium tuberculosis. Bioorg. Med. Chem. Lett. 2012; 22: 2902-2905. Abstract
  6. Sureram S, Wiyakrutta S, Ngamrojanavanich N, Mahidol C, Ruchirawat S, Kittakoop P. Depsidones, Aromatase Inhibitors and Radical Scavenging Agents from the Marine-derived Fungus Aspergillus unguis CRI282-03. Planta Med. 2012; 78: 582-588. Abstract
  7. Kaweetripob W, Mahidol C, Prachyawarakorn V, Prawat H, Ruchirawat S. 5-Formylfurfuryl esters from Duabanga grandiflora. Phytochemistry 2012; 76: 78-82. Abstract
  8. Wittayalai S, Sathalalai S, Thorroad S, Worawittayanon P, Ruchirawat S, Thasana N. Lycophlegmariols A-D: Cytotoxic Serratene Triterpenoids from the Club Moss Lycopodium phlegmaria L. Phytochemistry 2012; 76: 117-123. Abstract
  9. Worayuthakarn R, Nealmongkol P, Ruchirawat S, Thasana N. Synthesis of Benzoindoloquinolizines via a Cu(I)-mediated C–N Bond Formation. Tetrahedron 2012; 68: 2864-2875. Abstract
  10. Prachayasittikul S, Worachartcheewan A, Yainoy S, Lomchoey N, Kittiphatcharin P, Ruchirawat S, Prachayasittikul V. Antioxidant and antimicrobial activities of Saraca thaipingensis Cantley ex Prain. Asian Pac. J. Trop. Biomed. 2012; 2: S796-S799. Abstract
  11. Disadee W, Mahidol C, Sahakitpichan P, Sitthimonchai S, Ruchirawat S, Kanchanapoom T. Unprecedented Furan-2-carbonyl C-Glycosides and Phenolic Diglycosides from Scleropyrum pentandrum. Phytochemistry 2012; 74: 115-122. Abstract
  12. Worawittayanon P, Ruadreo J, Disadee W, Sahakitpichan P, Sitthimonchai S, Thasana N, Ruchirawat S, Kanchanapoom T. Iridoid and Flavone Glycosides from Asystasia gangetica subsp. micrantha and Asystasia salicifolia and Their Antioxidant Activities. Biochem. Syst. Ecol. 2012; 40: 38-42. Abstract
  13. Adachi M, Higuchi K, Thasana N, Yamada H, Nishikawa T. Stereocontrolled Synthesis of an Indole Moiety of Sespendole and Stereochemical Assignment of the Side Chain. Org. Lett. 2012; 14: 114-117. Abstract

2011

  1. Radomkit S, Sarnpitak P, Tummatorn J, Batsomboon P, Ruchirawat S, Ploypradith P. Pt(IV)-catalyzed generation and [4+2]-cycloaddition reactions of o-quinone methides. Tetrahedron 2011; 67: 3904–3914. Abstract
  2. Bunrit A, Ruchirawat S, Thongsornkleeb C. A Simple Microwave-assisted Preparation of 2-Bromo-1-alkenes from 1-Alkynes using the LiBr–TMSCl–TEAB Reagent System. Tetrahedron Lett. 2011; 52: 3124–3127. Abstract
  3. Sahakitpichan P, Disadee W, Ruchirawat S, Kanchanapoom T. 3-Hydroxydihydrobenzofuran Glucosides from Gnaphalium polycaulon. Chem. Pharm. Bull. (Tokyo) 2011; 59: 1160-1162. Abstract
  4. Bajgai SP, Prachyawarakorn V, Mahidol C, Ruchirawat S, Kittakoop P. Hybrid Flavan-Chalcones, Aromatase and Lipoxygenase Inhibitors, from Desmos cochinchinensis. Phytochemistry 2011; 72: 2062-2067. Abstract
  5. Ingavat N, Mahidol C, Ruchirawat S, Kittakoop P. Asperaculin A, a Sesquiterpenoid from a Marine-derived Fungus, Aspergillus aculeatus. J. Nat. Prod. 2011; 74: 1650-1652. Abstract
  6. Tianpanich K, Prachya S, Wiyakrutta S, Mahidol C, Ruchirawat S, Kittakoop P. Radical Scavenging and Antioxidant Activities of Isocoumarins and a Phthalide from the Endophytic Fungus Colletotrichum sp. J. Nat. Prod. 2011; 74: 79-81. Abstract
  7. Antia BS, Aree T, Kasettrathat C, Wiyakrutta S, Ekpa OD, Ekpe UJ, Mahidol C, Ruchirawat S, Kittakoop P. Itaconic Acid Derivatives and Diketopiperazine from the Marine-derived Fungus Aspergillus aculeatus CRI322-03. Phytochemistry 2011; 72: 816-820. Abstract
  8. Sahakitpichan P, Mahidol C, Disadee W, Ruchirawat S, Kanchanapoom T. Unusual Glycosides of Pyrrole Alkaloid and 4'-Hydroxyphenylethanamide from Leaves of Moringa oleifera. Phytochemistry 2011; 72: 791-795. Abstract
  9. Kanintronkul Y, Worayuthakarn R, Thasana N, Winayanuwattikun P, Pattanapanyasat K, Surarit R, Ruchirawat S, Svasti J. Overcoming Multidrug Resistance in Human Lung Cancer with Novel Benzo[a]quinolizin-4-ones. Anticancer Res. 2011; 31: 921-927. Abstract

2010

  1. Antia BS, Pansanit A, Ekpa OD, Ekpe UJ, Mahidol C, Kittakoop P. Alpha-Glucosidase Inhibitory, Aromatase Inhibitory, and Antiplasmodial Activities of a Biflavonoid GB1 from Garcinia kola Stem Bark. Planta Med. 2010; 76: 276-277. Abstract
  2. Tummatorn J, Ruchirawat S, Ploypradith P. A Convergent General Strategy for the Functionalized 2-Aryl Cycloalkyl-Fused Chromans: Intramolecular Hetero-Diels-Alder Reactions of ortho-Quinone Methides. Chem. Eur. J. 2010; 16: 1445-1448. Abstract
  3. Kamolkijkarn P, Prasertdee T, Netirojjanakul C, Sarnpitak P, Ruchirawat S, Deechongkit S. Synthesis, Biophysical, and Biological Studies of Wild-type and Mutant Psalmopeotoxins-Anti-malarial Cysteine Knot Peptides from Psalmopoeus cambridgei. Peptides 2010; 31: 533-540. Abstract
  4. Chittchang M, Gleeson MP, Ploypradith P, Ruchirawat S. Assessing the Drug-likeness of Lamellarins, a Marine-derived Natural Product Class with Diverse Oncological Activities. Eur. J. Med. Chem. 2010; 45: 2165-2172. Abstract
  5. Parks J, Gyeltshen T, Prachyawarakorn V, Mahidol C, Ruchirawat S, Kittakoop P. Glutarimide Alkaloids and a Terpenoid Benzoquinone from Cordia globifera. J. Nat. Prod. 2010; 73: 992-994. Abstract
  6. Thasana N, Prapagdee B, Rangkadilok N, Sallabhan R, Aye SL, Ruchirawat S, Loprasert S. Bacillus subtilis SSE4 Produces Subtulene A, a New Lipopeptide Antibiotic Possessing an Unusual C15 Unsaturated Beta-amino acid. FEBS Lett. 2010; 584: 3209-3214. Abstract
  7. Gleeson MP, Deechongkit S, Ruchirawat S. Molecular Dynamics Investigation of Psalmopeotoxin I. Probing the Relationship between 3D Structure, Anti-malarial Activity and Thermal Stability. J. Mol. Model. 2011; 17: 769-775. Abstract
  8. Charoenchai P, Vajrodaya S, Somprasong W, Mahidol C, Ruchirawat S, Kittakoop P. Part 1: Antiplasmodial, Cytotoxic, Radical Scavenging and Antioxidant Activities of Thai Plants in the Family Acanthaceae. Planta Med. 2010; 76: 1940-1943. Abstract
  9. Boonya-Udtayan S, Yotapan N, Woo C, Bruns CJ, Ruchirawat S, Thasana N. Synthesis and Biological Activities of Azalamellarins. Chem. Asian J. 2010; 5: 2113-2123. Abstract
  10. Aree T, Antia BS, Ekpab OD, Kittakoop P. Paraherquamide E. Acta Cryst. 2010; E66: o2227. Abstract
  11. Chomcheon P, Wiyakrutta S, Aree T, Sriubolmas N, Ngamrojanavanich N, Mahidol C, Ruchirawat S, Kittakoop P. Curvularides A-E: Antifungal Hybrid Peptide-Polyketides from the Endophytic Fungus Curvularia geniculata. Chemistry 2010; 16: 11178-11185. Abstract
  12. Sahakitpichan P, Disadee W, Ruchirawat S, Kanchanapoom T. L-(-)-(N-trans-Cinnamoyl)-arginine, an Acylamino Acid from Glinus oppositifolius (L.) Aug. DC. Molecules 2010; 15: 6186-6192. Abstract

2009

  1. Chomcheon P, Wiyakrutta S, Sriubolmas N, Ngamrojanavanich N, Mahidol C, Ruchirawat S, Kittakoop P. Metabolites from the Endophytic Mitosporic Dothideomycete sp. LRUB20. Phytochemistry 2009; 70: 121-127. Abstract
  2. Chomcheon P, Wiyakrutta S, Sriubolmas N, Ngamrojanavanich N, Kengtong S, Mahidol C, Ruchirawat S, Kittakoop P. Aromatase Inhibitory, Radical Scavenging, and Antioxidant Activities of Depsidones and Diaryl Ethers from the Endophytic Fungus Corynespora cassiicola L36. Phytochemistry 2009; 70: 407-413. Abstract
  3. Chittchang M, Batsomboon P, Ruchirawat S, Ploypradith P. Cytotoxicities and Structure-activity Relationships of Natural and Unnatural Lamellarins towards Cancer Cell Lines. ChemMedChem 2009; 4: 457-465. (highlighted as the frontispiece of the issue) Abstract
  4. Batsomboon P, Phakhodee W, Ruchirawat S, Ploypradith P. Generation of o-Quinone Methides by p-TsOH on Silica and Their Hetero-Diels-Alder Reactions with Styrenes. J. Org. Chem. 2009; 74: 4009-4012. Abstract
  5. Tangdenpaisal K, Sualek S, Ruchirawat S, Ploypradith P. Factors Affecting Orthogonality in the Deprotection of 2,4-Di-protected Aromatic Ethers Employing Solid-Supported Acids. Tetrahedron 2009; 65: 4316-4325. Abstract
  6. Dettrakul S, Surerum S, Rajviroongit S, Kittakoop P. Biomimetic Transformation and Biological Activities of Globiferin, a Terpenoid Benzoquinone from Cordia globifera. J. Nat. Prod. 2009; 72, 861–865. Abstract
  7. Mahidol C, Prawat H, Sangpetsiripan S, Ruchirawat S. Bioactive scalaranes from the Thai sponge Hyrtios gumminae. J. Nat. Prod. 2009; 72:1870-1874. Abstract
  8. Ingavat N, Dobereiner J, Wiyakrutta S, Mahidol C, Ruchirawat S, Kittakoop P. Aspergillusol A, an Alpha-Glucosidase Inhibitor from the Marine-derived Fungus Aspergillus aculeatus. J. Nat. Prod. 2009; 72: 2049-2052. Abstract
  9. Aree T, Surerum S, Ngamrojanavanich N, Kittakoop P. (E)-2,4,7-Trichloro-3-hydroxy-8-methoxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-11H-dibenzo[b,e][1,4]dioxepin-11-one monohydrate (nidulin monohydrate). Acta Cryst. 2009; E65: o2470-o2471. Abstract

2008

  1. Prachyawarakorn V, Mahidol C, Sureram S, Sangpetsiripan S, Wiyakrutta S, Ruchirawat S, Kittakoop P. Diketopiperazines and Phthalides from a Marine Derived Fungus of the Order Pleosporales. Planta Med. 2008; 74: 69-72. Abstract
  2. Worayuthakarn R, Boonya-udtayan S, Arom-oon E, Ploypradith P, Ruchirawat S, Thasana N. Synthesis of Unsymmetrical Benzil Licoagrodione. J. Org. Chem. 2008; 73: 7432-7435. Abstract
  3. Kasettrathat C, Ngamrojanavanich N, Wiyakrutta S, Mahidol C, Ruchirawat S, Kittakoop P. Cytotoxic and Antiplasmodial Substances from Marine-derived Fungi, Nodulisporium sp. and CRI247-01. Phytochemistry 2008; 69: 2621-2626. Abstract
  4. Thasana N, Bjerke-Kroll B, Ruchirawat S. A Facile Synthesis of Telisatin A via Microwave-promoted Annulation and Reformatsky Reaction. Synlett 2008; 505-508. Abstract

2007

  1. Prachya S, Wiyakrutta S, Sriubolmas N, Ngamrojanavanich N, Mahidol C, Ruchirawat S, Kittakoop P. Cytotoxic Mycoepoxydiene Derivatives from an Endophytic Fungus Phomopsis sp. isolated from Hydnocarpus anthelminthicus. Planta Med. 2007; 73: 1418-1420. Abstract
  2. Youngsa-ad W, Ngamrojanavanich N, Mahidol C, Ruchirawat S, Prawat H, Kittakoop P. Diterpenoids from the Roots of Croton oblongifolius. Planta Med. 2007; 73: 1491-1494. Abstract
  3. Thasana N, Worayuthakarn R, Kradanrat P, Hohn E, Young L, Ruchirawat S. Copper(I)-mediated and Microwave-assisted C(aryl)-O(carboxylic) Coupling: Synthesis of Benzopyaranones and Isolamellarin Alkaloids. J. Org. Chem. 2007; 72, 9379-9382. Abstract