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Research Highlight

Research Highlight

Environmental Toxicology

Arsenic disrupts neuronal insulin signaling through increasing free PI3K-p85 and decreasing PI3K activity

Sulfur amendments to soil decrease inorganic arsenic accumulation in rice grain under flooded and nonflooded conditions: Insights from temporal dynamics of porewater chemistry and solid-phase arsenic solubility

Prolonged arsenic exposure increases tau phosphorylation in differentiated SH-SY5Y cells: The contribution of GSK3 and ERK1/2

Inhibition of T-cell-mediated immune response via the PD-1/ PD-L1 axis in cholangiocarcinoma cells

Interactive effects of Andrographis paniculata extracts and cancer chemotherapeutic 5-Fluorouracil on cytochrome P450s expression in human hepatocellular carcinoma HepG2 cells

Applied Biological Sciences

HMP-S7 is a novel anti-leukemic peptide discovered from human milk

Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure–activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study

The effects of agomelatine on endoplasmic reticulum stress related to mitochondrial dysfunction in hippocampus of aging rat model

A Synopsis of Multitarget Potential Therapeutic Effects of Huperzine A in Diverse Pathologies–Emphasis on Alzheimer’s Disease Pathogenesis

Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFκB signaling pathway in the mouse hippocampus

Melatonin protects against methamphetamine-induced Alzheimer’s disease-like pathological changes in rat hippocampus

5,6,7,4′-Tetramethoxyflavanone alleviates neurodegeneration in a dexamethasone-induced neurodegenerative mouse model through promotion of neurogenesis via the Raf/ERK1/2 pathway

Melatonin reverts methamphetamine-induced learning and memory impairments and hippocampal alterations in mice

Melatonin attenuates reactive astrogliosis and glial scar formation following cerebral ischemia and reperfusion injury mediated by GSK-3β and RIP1K

Melatonin receptor as a drug target for neuroprotection

Role of melatonin on virus-induced neuropathogenesis—a concomitant therapeutic strategy to understand SARS-CoV-2 infection

Ischemic stroke, obesity, and the anti-inflammatory role of melatonin

Over-Expression of Hypochlorite Inducible Major Facilitator Superfamily (MFS) Pumps Reduces Antimicrobial Drug Susceptibility by Increasing the Production of MexXY Mediated by ArmZ in Pseudomonas aeruginosa

Modified recombinant human erythropoietin with potentially reduced immunogenicity

NieR is the repressor of a NaOCl-inducible efflux system in Agrobacterium tumefaciens C58

An Expeditious Modular Hybrid Strategy for the Diversity-Oriented Synthesis of Lamellarins/Azalamellarins with Anticancer Cytotoxicity

Roles of autophagy in relation to mitochondrial stress responses of HeLa cells to lamellarin cytotoxicity

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