August 2015

Over the last decade, in vitro models have become moresophisticated and are at a stage where they can provide aneffective alternative to in vivo experiments. Replacing AnimalModels provides scientists and technicians with a practical,integrated guide to developing culture-based alternatives to invivo experiments. (kinokuniya.com)

Explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. This book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials.

 

This book explores bioconjugate properties and applications of polymers, dendrimers, lipids, nanoparticles, and nanotubes Bioconjugation has enabled breakthroughs across many areas of industry and biomedicine. With its emphasis on synthesis, properties and applications, this book enables readers to understand the connection between chemistry and the biological application of bioconjugated materials. Its detailed descriptions of methods make it possible for researchers to fabricate and take full advantage of bioconjugates for a broad range of applications. Moreover, the book sets the foundation for the development of new applications, including assays, imaging, biosensors, drug delivery, and diagnostics. Chemistry of Bioconjugates features contributions from an international team of leading experts and pioneers in the field. These contributions reflect the authors firsthand laboratory experience as well as a thorough review of the current literature. The books six sections examine: general methods of bioconjugation; polymer bioconjugates; organic nanoparticle-based bioconjugates; inorganic nanomaterial bioconjugates, including metals and metal oxides; cell-based, hydrogel/microgel, and glyco-bioconjugates; and characterization, physico-(bio)chemical properties, and applications of bioconjugates. This comprehensive exploration of bioconjugates includes discussions of polymers, dendrimers, lipids, nanoparticles, and nanotubes. References at the end of each chapter serve as a gateway to the most important original research findings and reviews in the field. By drawing together and analyzing all the latest chemical methods and research findings on the physico-chemical and biochemical properties of bioconjugates, Chemistry of Bioconjugates sheds new light on the significance and potential of bioconjugation. The book is recommended for organic and polymer chemists, biochemists, biomaterial scientists, carbohydrate chemists, biophysicists, bioengineers, and drug and gene delivery scientists. (kinokuniya.com)

Integrative Medical Biochemistry Examination and Board Review is a fast and effective way for you to prepare for regular course examinations in biochemistry and medical biochemistry, as well as medical board exams and the USMLE Step 1. A unique feature of this review is the integration of medical biochemistry with physiology, pathophysiology, pathology, and anatomy, making it perfect for today’s rapidly changing medical school curriculum. Integrative Medical Biochemistry Examination and Board Review is logically divided into four sections. (kinokuniya.com)

Hematology-Oncology Therapy, Second Edition is an up-to-date, comprehensive therapy guide that delivers more than 500 treatment regimens in a succinct, uniform manner. The unique tabular design allows you to instantly locate and implement the proper treatment regimen. Supported by the latest practice guidelines, peer-reviewed literature, and the opinion of experts, Hematology-Oncology Therapy integrates extensive information that is critical to both office- and hospital-based practice of hematology and oncology. (kinokuniya.com)

This text offers the most respected book available for scientific information about dioxins, dibenzofurans, and PCBs. The new edition combines chapters on the classical dioxins and PCBs with new and emerging toxic pollutants. This edition also updates the science involved in the dioxin and PCB literature while adding new chapters on toxic pollutants such as brominated flame retardants, phthalates, and perfluorinated chemicals. A comprehensive resource, this book provides, in one volume, essential information about these compounds written by some of the most respected and cited scientists in their fields. (kinokuniya.com)

Over the last ten years the subject of toxicology has changed dramatically, moving from a discipline which was once firmly wedded to traditional methods to one which is keen to embrace the innovative techniques emerging from the developing fields of cell culture and molecular biology. There is an acute need for this to be reflected in a paradigm shift which takes advantage of the opportunities offered by modern developments in the life sciences, including new in vitro and in silico approaches, alternative whole organism (non-mammalian) models and the exploitation of omics methods, high throughput screening (HTS) techniques and molecular imaging technologies.
This concise, accessible introduction to the field includes the very latest concepts and methodologies. It provides MSc, PhD and final year undergraduate students in pharmacy, biomedical and life sciences, as well as individuals starting out in the cosmetics, consumer products, pharmaceutical and testing industries, with everything they need to know to get to grips with the fast moving field of toxicology and the current approaches used in the risk assessment of drugs and chemicals. (kinokuniya.com)

This book describes the principles, methods, and applications of PBPK modeling in the pharmaceutical industry. It addresses a growing need, as more and more pharma companies are integrating PBPK into their lead selection cycle and clinical development. Moving easily from theory to practice, the author presents coverage of both the principles and applications of PBPK modeling, exposing the power of this tool to improve the process of drug discovery and development. With end-of-chapter glossaries, extensive bibliographic references, and an emphasis on practical applications, this resource provides a much-needed single source for this important area. (kinokuniya.com)

For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals. (kinokuniya.com)

Steroid Dimers: Chemistry and Applications in Drug Design and Delivery provides an up-to-date overview on the chemistry and applications of steroid dimers of natural and synthetic origins.The book includes easy-to-follow synthetic protocols for various classes of important dimeric steroids, source details, valuable spectroscopic data and depiction of unique structural features ofnatural steroidal dimers, and the Structure-Activity-Relationships(SARs) of some pharmacologically active dimeric steroids. (kinokuniya.com)

Emphasizing the applications of chemistry and minimizing complicated mathematics, “General, Organic, And Biological Chemistry, 6/e, International Edition” is written throughout to help students succeed in the course and master the biochemistry content so important to their future careers. The Sixth Edition’s clear explanations, visual support, and effective pedagogy combine to make the text ideal for allied health majors. Early chapters focus on fundamental chemical principles while later chapters build on the foundations of these principles. Mathematics is introduced at point-of-use and only as needed. (kinokuniya.com)

Ionic Liquids in Biotransformations and Organocatalysis is the first book to provide a multidisciplinary approach and overview of the fundamentals of ionic liquids and their interaction with proteins in diverse applications such as paint additives, reactive gas transport, nanomaterials synthesis, and hydrogen storage.

 

This book addresses the use of ionic liquids in biotransformation and organocatalysis. Its major parts include: an overview of the fundamentals of ionic liquids and their interactions with proteins and enzymes; the use of ILs in biotransformations; non-solvent applications such as additives, membranes, substrate anchoring, and the use of ILs in organocatalysis (from solvents to co-catalysts and new reactivities, as well as non-solvent applications such as anchoring and immobilization). (kinokuniya.com)

This is a comprehensive source of information on the application of ion chromatography (IC) in the analysis of pharmaceutical drugs and biologicals. This book, with contributors from academia, pharma, the biotech industry, and instrument manufacturing, presents the different perspectives, experience, and expertise of the thought leaders of IC in a comprehensive manner. It explores potential IC applications in different aspects of product development and quality control testing. In addition, an appendix section gives information on critical physical and chromatographic parameters related to IC and information on current manufacturers of IC systems, columns, and other components. (kinokuniya.com)

Extraction processes are essential steps in numerous industrial applications from perfume over pharmaceutical to fine chemical industry. Nowadays, there are three key aspects in industrial extraction processes: economy and quality, as well as environmental considerations. This book presents a complete picture of current knowledge on green extraction in terms of innovative processes, original methods, alternative solvents and safe products, and provides the necessary theoretical background as well as industrial application examples and environmental impacts. Each chapter is written by experts in the field and the strong focus on green chemistry throughout the book makes this book a unique reference source. This book is intended to be a first step towards a future cooperation in a new extraction of natural products, built to improve both fundamental and green parameters of the techniques and to increase the amount of extracts obtained from renewable resources with a minimum consumption of energy and solvents, and the maximum safety for operators and the environment (kinokuniya.com)

Featuring a superb compilation of chapters related to infectious diseases that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. (kinokuniya.com)