Publications

Independent:

  1. Chaisan, N.; Ruengsangtongkul, S.; Thongsornkleeb, C.;* Tummatorn, J.; Ruchirawat, S. Dihalooxygenation of Alkynes and Alkynols: Preparation of 2,2-Dihaloketones and gem-Dihalolactols. Synlett2022Full Text (Accepted Manuscripts)  
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  2. Ruengsangtongkul, S.; Kuribara, T.; Chaisan, N.; Tummatorn, J.; Thongsornkleeb,C.;* Ruchirawat, S. Ceric Ammonium Nitrate‐Promoted Oxidative Coupling of Terminal Alkynes and 1,3‐Ketoesters: A Synthesis of Unsymmetrical 1,1,2‐Triacylalkenes. Synlett2022Full Text (Accepted Manuscripts)  
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  3. Thongsornkleeb, C.; Tummatorn, J.;* Ruchirawat, S. A Compilation of Synthetic Strategies to Access the Most Utilized Indoloquinoline Motifs. Chem. Asian J.2022Full Text (Accepted Articles) 
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  4. Laohapaisan, P.; Lumyong, K.; Tummatorn, J.;* Thongsornkleeb, C.; Chatwichien, J.; Supantanapong, N.; Ruchirawat, S. Ag(I)-Catalyzed/Acid-Mediated Cascade Cyclization of ortho-Alkynylaryl-1,3-dicarbonyls to Access Arylnaphthalenelactones and Furanonaphthol Libraries via Aryl-Disengagement. Chem. Asian J. 2021 Full Text (Early View)
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  5. Rodphon, W.; Laohapaisan, P.; Supantanapong, N.; Reamtong, O.; Ngiwsara, L.; Lirdprapamongkol, K.;* Thongsornkleeb, C.; Khunnawutmanotham, N.; Tummatorn, J.;* Svasti, J.; Ruchirawat, S. Synthesis of Isocryptolepine-Triazole Adducts and Evaluation of Their Cytotoxic Activity. ChemMedChem 2021, 16, 3750-3762. Full Text
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  6. Reamtong, O.; Lapmanee, S.; Tummatorn, J.;* Palavong, N.; Thongsornkleeb, C.; Ruchirawat, S. Synthesis of Benzoazepine Derivatives via Azide Rearrangement and Evaluation of Their Antianxiety Activities. ACS Med. Chem. Lett. 2021, 12, 1449-1458. Full Text (Selected as an issue’s cover)
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  7. Jaithum, K.; Tummatorn, J.;* Boekfa, B.; Thongsornkleeb, C.; Chainok, K.; Ruchirawat, S. Diastereoselective Synthesis of Spirocyclic Ether from ortho-Carbonylarylacetylenols via Silver-Catalyzed Cyclization under Acidic Conditions. Adv. Synth. Catal. 2021, 363, 3812-3834. Full Text
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  8. Thongsornkleeb, C.; Tummatorn, J.;* Ruchirawat, S. Utilization of ortho-alkynylarylcarbonyl derivatives for creating structurally diverse chemical compounds. Org. Biomol. Chem. 2021, 19, 5982-5998. Full Text
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  9. Punjajom, K.; Tummatorn, J.; Ruchirawat, S.; Thongsornkleeb, C.* PdCl2‐Catalyzed Oxidative Cyclization of N‐(2’‐Alkynylaryl)‐1,3‐ketoamides: Synthesis of 3,4‐Diacyl‐2‐Quinolones. Asian J. Org. Chem. 2021, 10, 906-917. Full Text
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  10. Chaisan, N.; Ruengsangtongkul, S.; Tummatorn, J.; Ruchirawat, S.; Chainok, K.; Thongsornkleeb, C.* Dibrominative Spirocyclization of 2-Butynolyl Anilides: Synthesis of gem-Dibromospirocyclic Benzo[d][1,3]oxazines and Their Application in the Synthesis of 4H-Furo[3,2-b]indoles. J. Org. Chem. 2021, 86, 4671–4698. Full Text
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  11. Rodphon, W.; Thongsornkleeb, C.; Tummatorn, J.;* Ruchirawat, S. Synthesis of 4‐Acylchromene via Highly Chemoselective Iodine‐Catalyzed Cyclization of Alkynylarylether Dimethylacetals. Chem. Asian J. 2020, 15, 3475-3486. Full Text
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  12. Akkachairin, B.; Rodphon, W.; Reamtong, O.; Mungthin, M.; Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S. Synthesis of neocryptolepines and carbocycle-fused quinolines and evaluation of their anticancer and antiplasmodial activities. Bioorg. Chem. 2020, 98, Article 103732. Full Text
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  13. Norseeda, K.; Chaisan, N.; Thongsornkleeb, C.;* Tummatorn, J.; Ruchirawat, S. Metal-Free Synthesis of 4-Chloroisocoumarins by TMSCl-Catalyzed NCS-Induced Chlorinative Annulation of 2-Alkynylaryloate Esters. J. Org. Chem. 2019, 84, 16222–16236. Full Text
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  14. Laohapaisan, P.; Chuangsoongnern, P.; Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S. Divergent Synthesis of 3-Hydroxyfluorene and 4-Azafluorene Derivatives from ortho-Alkynylarylketones. J. Org. Chem. 2019, 84, 14451–14460. Full Text (Selected as an issue’s cover)
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  15. Tummatorn, J.;* Punjajom, K.; Rodphon, W.; Ruengsangtongkul, S.; Chaisan, N.; Lumyong, K.; Thongsornkleeb, C.; Nimnual, P.; Ruchirawat, S. Chemoselective Synthesis of 1,1-Disubstituted Vinyl Triflates from Terminal Alkynes Using TfOH in the Presence of TMSN3. Org. Lett. 2019, 21, 4694–4697. Full Text
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  16. Nimnual, P.; Tummatorn, J.;* Boekfa, B.; Thongsornkleeb, C.; Ruchirawat, S.; Piyachat, P.; Punjajom, K. Construction of 5-Aminotetrazoles via in Situ Generation of Carbodiimidium Ions from Ketones Promoted by TMSN3/TfOH. J. Org. Chem. 2019, 84, 5603–5613. Full Text
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  17. Ruengsangtongkul, S.; Chaisan, N.; Thongsornkleeb, C.;* Tummatorn, J.; Ruchirawat, S. Rate Enhancement in CAN-Promoted Pd(PPh3)2Cl2-Catalyzed Oxidative Cyclization: Synthesis of 2-Ketofuran-4-carboxylate Esters. Org. Lett. 2019, 21, 2514–2517. Full Text (Selected as an issue’s cover)
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  18. Supantanapong, N.; Chuangsoongnern, P.; Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S. One-pot sequential synthesis of 3-carbonyl-4-arylbenzo[f]indole and 3-carbonyl-4-arylnaphthofuran fluorophores. Org. Chem. Front. 2019, 6, 1340–1355. Full Text (Selected as the issue’s front cover)
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  19. Akkachairin, B.; Tummatorn, J.;* Khamsuwan, N.; Thongsornkleeb, C.; Ruchirawat, S. Domino N2–Extrusion–Cyclization of Alkynylarylketone Derivatives for the Synthesis of Indoloquinolines and Carbocycle-Fused Quinolines. J. Org. Chem. 2018, 83, 11254–11268. Full Text
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  20. Nimnual, P.; Norseeda, K.; Akkachairin, B.; Tummatorn, J.;* Laohapaisan, P.; Supantanapong, N.; Chuangsoongnern, P.; Thongsornkleeb, C.; Sittihan, S.; Ruchirawat, S.; Rodphon, W. Synthesis of β‐Naphthols and Naphthofuranones from ortho‐Alkynylarylketones via Sequential AgTFA‐Catalyzed Ketonization–Intramolecular Aldol Condensation: A Total Synthesis of Negundin A. Asian J. Org. Chem. 2018, 7, 932–945. Full Text
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  21. Chaisan, N.; Kaewsri, K.; Thongsornkleeb, C.;* Tummatorn, J.; Ruchirawat, S. PtCl4-catalyzed cyclization of N-acetyl-2-alkynylanilines: A mild and efficient synthesis of N-acetyl-2-substituted indoles. Tetrahedron Lett. 2018, 59, 675–680. Full Text
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  22. Kaewsri, W.; Norseeda, K.; Ruengsangtongkul, S.; Chaisan, N.; Thongsornkleeb, C.;* Tummatorn, J.; Ruchirawat, S. Synthesis of 2-Cyclohexenone-2-carboxylate and 4-Chloro-2-cyclohexenone-2-carboxylate Derivatives by Cyclization of Alkyne-Tethered 1,3-Ketoesters. Asian J. Org. Chem. 2018, 7, 203–211. Full Text
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  23. Chuangsoongnern, P.; Surinrach, C.; Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S. Iodine-Mediated Cyclization of ortho-Alkynylaryl Ketones for the Synthesis of Indenone Derivatives. Eur. J. Org. Chem. 2017, 2017, 5102–5109. Full Text
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  24. Akkachairin, B.; Tummatorn, J.;* Supantanapong, N.; Nimnual, P.; Thongsornkleeb, C.; Ruchirawat, S. Silver-Catalyzed Cyclization of ortho-Carbonylarylacetylenols for the Synthesis of Dihydronaphthofurans. J. Org. Chem. 2017, 82, 3727–3740. Full Text
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  25. Jantaree, P.; Lirdprapamongkol, K.;* Kaewsri, W.; Thongsornkleeb, C.; Choowongkomon, K.; Atjanasuppat, K.; Ruchirawat, S.; Svasti, J. Homodimers of Vanillin and Apocynin Decrease the Metastatic Potential of Human Cancer Cells by Inhibiting the FAK/PI3K/Akt Signaling Pathway. J. Agric. Food Chem. 2017, 65, 2299–2306. Full Text
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  26. Kaewsri, W.; Thongsornkleeb, C.;* Tummatorn, J.; Ruchirawat, S. Isomerizable (E/Z)-alkynyl-O-methyl oximes employing TMSCl–NCS in chlorinative cyclization for the direct synthesis of 4-chloroisoxazoles. RSC Adv. 2016, 6, 48666–48675. Full Text
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  27. Norseeda, K.; Tummatorn, J.;* Krajangsri, S.; Thongsornkleeb, C.; Ruchirawat, S. Synthesis of 6-Alkyl-6 H-benzo[c]chromene Derivatives by Cyclization/Selective Ether Cleavage in One Pot: Total Synthesis of Cannabinol. Asian J. Org. Chem. 2016, 5, 792–800. Full Text
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  28. Nimnual, P.; Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S. Utility of Nitrogen Extrusion of Azido Complexes for the Synthesis of Nitriles, Benzoxazoles and Benzisoxazoles. J. Org. Chem. 2015, 80, 8657–8667. Full Text
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  29. Tummatorn, J.;* Poonsilp, P.; Nimnual, P.; Janprasit, J.; Thongsornkleeb, C.; Ruchirawat, S. Regioselective Synthesis of 3‑Bromoquinoline Derivatives and Diastereoselective Synthesis of Tetrahydroquinolines via Acid-Promoted Rearrangement of Arylmethyl Azides. J. Org. Chem. 2015, 80, 4516–4525. Full Text
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  30. Aroonkit, P.; Thongsornkleeb, C.;* Tummatorn, J.;* Krajangsri, S.; Mungthin, M.; Ruchirawat, S. Synthesis of isocryptolepine analogues and their structure–activity relationship studies as antiplasmodial and antiproliferative agents. Eur. J. Med. Med. 2015, 94, 56–62. Full Text
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  31. Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S.; Thongaram, P.; Kaewmee, B. Convenient and Direct Azidation of sec-Benzyl Alcohols by Trimethylsilyl Azide with Bismuth(III) Triflate Catalyst. Synthesis 2015, 47, 323–329. Full Text
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  32. Tummatorn, J.;* Krajangsri, S.; Norseeda, K.; Thongsornkleeb, C.; Ruchirawat, S. A new synthetic approach to 6-unsubstituted phenanthridine and phenanthridine-like compounds under mild and metal-free conditions. Org. Biomol. Chem. 2014, 12, 5077–5081. Full Text
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  33. Maibunkaew, T.; Thongsornkleeb, C.;* Tummatorn, J.; Bunrit, A.; Ruchirawat, S. Practical and Metal-Free Electrophilic Aromatic Halogenation by Interhalogen Compounds Generated in situ from N-Halosuccinimide and Catalytic TMSCl. Synlett 2014, 25, 1769–1775. Full Text
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  34. Tummatorn, J.;* Gleeson, M. P.; Krajangsri, S.; Thongsornkleeb, C.; Ruchirawat, S. ZrCl4-promoted facile synthesis of indole derivatives. RSC Adv. 2014, 4, 20048–20052. Full Text
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  35. Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S.; Gettongsong, T. Synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters from arylmethyl azides via a domino process. Org. Biomol. Chem. 2013, 11, 1463–1467. Full Text
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  36. Thongsornkleeb, C.;* Rabten, W.; Bunrit, A.; Tummatorn, J.; Ruchirawat, S. Facile access to 2,5-disubstituted-4-chloromethyl-3-iodofuran derivatives via ICl-mediated cyclization of 1-alkyl-2-alkynylallylic alcohols. Tetrahedron Lett. 2012, 53, 6615–6619. Full Text
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  37. Tummatorn, J.;* Thongsornkleeb, C.; Ruchirawat, S. Acid-promoted rearrangement of arylmethyl azides: applications toward the synthesis of N-arylmethyl arenes and polycyclic heteroaromatic compounds. Tetrahedron 2012, 68, 4732–4739. Full Text
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  38. Bunrit, A.; Ruchirawat, S.; Thongsornkleeb, C.* A simple microwave-assisted preparation of 2-bromo-1-alkenes from 1-alkynes using the LiBr–TMSCl–TEAB reagent system. Tetrahedron Lett. 2011, 52, 3124–3127. Full Text
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Pre-Independent:

  1. Fearnley, S. P.;* Thongsornkleeb, C. Oxazolone Cycloadducts as Heterocyclic Scaffolds for Alkaloid Construction: Synthesis of (±)-2-epi-Pumiliotoxin C. J. Org. Chem. 2010, 75, 933–936. Full Text
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  2. Thongsornkleeb, C.; Danheiser, R. L.* A Practical Method for the Synthesis of 2-Alkynylpropenals. J. Org. Chem. 2005, 70, 2364–2367. Full Text
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  3. Bailey, W. F.;* England, M. D.; Mealy, M. J.; Thongsornkleeb, C.; Teng, L. Facile O-Deallylation of Allyl Ethers via SN2′ Reaction with tert-Butyllithium. Org. Lett. 2000, 2, 489–491. Full Text
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Work Featured on Journal Covers

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Org. Lett. 2019, 21, 2514–2517. 		42.jpg
Org. Chem. Front. 2019, 6, 1340–1355. 		43.jpg
J. Org. Chem. 2019, 84, 14451–14460.
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ACS Med. Chem. Lett. 2021, 12, 1449–1458. 		asia202101322-toc-0001-m.jpg
Chem.Asia J.2022(Early View) 		asia202200124-toc-0001-m_journal_front_cover_.jpg
Chem.Asia J.2022(Early View)