RESEARCH IN CHEMICAL SCIENCES (CS)
2025
- Metabolomic Profiling and Anti-Helicobacter pylori Activity of Caulerpa lentillifera (Sea Grape) Extract
Author(s) : Chananchida Thacharoen, Thisirak Inkaewwong, Watthanachai Jumpathong, Pornchai Kaewsapsak, Thiravat Rattanapot, Tippapha Pisithkul.
Publications Date : 25 Jul 2025 - Designing Novel InhA Inhibitors for Antituberculosis Agents Using ab Initio Fragment Molecular Orbital Calculations
Author(s) : Thimpika Pornprom, Bongkochawan Pakamwong, Darunee Sukchit, Masayuki Yuguchi, Yoshinobu Nagura, Haruna Sabishiro, Nagomi Chimura, Auradee Punkvang, Paptawan Thongdee, Khomson Suttisintong, Prasat Kittakoop, Noriyuki Kurita, Pornpan Pungpo.
Publications Date : 21 Jul 2025 - An LC-MS Based Metabolomic Approach Coupled With Bioassay-Guided Fractionation to Identifying Bioactive Biflavonoids From Selaginella Willdenowii
Author(s) : Sutthida Wongsuwan, Watthanachai Jumpathong, Jaruwan Chatwichien, Wanlaya Thamnarak, Lukana Ngiwsara, Kriengsak Lirdprapamongkol, Jisnuson Svasti, Somsak Ruchirawat, Nopporn Thasana.
Publications Date : 21 Jul 2025 - Design, synthesis, in silico and in vitro evaluation of pyrrole-indole hybrids as dual tubulin and aromatase inhibitors with potent anticancer activities
Author(s) : Rungroj Saruengkhanphasit, Jaruwan Chatwichien, Lukana Ngiwsara, Kriengsak Lirdprapamongkol, Worawat Niwetmarin, Chatchakorn Eurtivong, Prasat Kittakoop, Jisnuson Svasti, Somsak Ruchirawat.
Publications Date : 30 Jun 2025 - Antiproliferative cassaine diterpenoid amines from the leaves and twigs of the traditional Thai medicinal plant Erythrophleum teysmannii (Kurz) Craib
Author(s) : Maria Orfanoudaki, Dongdong Wang, Lin Du, Somsak Ruchirawat, Prasat Kittakoop, Tanja Grkovic, Chulabhorn Mahidol, Barry R O'Keefe.
Publications Date : 27 Jun 2025 - Synthesis of Functionalized Benzo[h]Quinolines via Base-Catalyzed 1,4-Addition/Intramolecular Annulation Cascade
Author(s) : Wannaporn Disadee, M Paul Gleeson, Somsak Ruchirawat.
Publications Date : 23 Jun 2025 - Synthesis of Isoquinoline N-Oxides via Hypervalent Iodine-Mediated Oxidative Cyclization of Ketoximes with Alkenes
Author(s) : Aurapat Ngamnithiporn, Padon Chuentragool, Supakarn Punnita, Wachirawit Thitseesaeng, Teesuda Sirichai, Shinji Harada, Tetsuhiro Nemoto, Poonsakdi Ploypradith, Somsak Ruchirawat.
Publications Date : 05 Jun 2025 - Hybrid virtual screening identifies dipyrazole carboxamide derivatives as novel direct InhA inhibitors with antitubercular activity
Author(s) : Auradee Punkvang, Bongkochawan Pakamwong, Naruedon Phusi, Paptawan Thongdee, Kampanart Chayajarus, Jidapa Sangswan, Kanjana Pangjit, Khomson Suttisintong, Jiraporn Leanpolchareanchai, Poonpilas Hongmanee, Pitak Santanirand, James Spencer, Adrian J Mulholland, Sanya Sureram, Prasat Kittakoop, Pornpan Pungpo.
Publications Date : 28 May 2025 - Astraeusols A-E: lanostane-type triterpenes from the wild edible mushroom Astraeus asiaticus
Author(s) : Jedsada Maliwong, Nitirat Chimnoi, Natsajee Nualkaew, Somsak Ruchirawat, Tripetch Kanchanapoom.
Publications Date : 26 May 2025 - Cytotoxic, antibacterial, and aromatase inhibitory activities of cycloartane triterpenes and flavones from Gardenia obtusifolia
Author(s) : Wiriya Yaosanit, Surasak Prachya, Phanruethai Pailee, Theerawat Thananthaisong, Chulabhorn Mahidol, Poonsakdi Ploypradith, Nanthawan Reuk-Ngam, Panita Khlaychan, Supanna Techasakul, Somsak Ruchirawat, Vilailak Prachyawarakorn.
Publications Date : 01 May 2025 - Diterpenes as nitric oxide secretion inhibitors from Kaempferia koratensis rhizomes
Author(s) : Patcharin Kongwaen, Jutatip Boonsombat, Sanit Thongnest, Rapeepat Sangsuwan, Nedsai Uddin Babar, Tawit Suriyo, Chatphorn Theppitak, Kittipong Chainok, Jutamaad Satayavivad, Chulabhorn Mahidol, Somsak Ruchirawat.
Publications Date : 24 Apr 2025 - A Direct Route to Habiterpenol Synthesis Using Anticopalic Acid as a Chiral Pool Template
Author(s) : Sittisak Oekchuae, Pornsuda Chawengrum, Sanit Thongnest, Jutatip Boonsombat, Jitnapa Sirirak, Pornpuk Booranaseensuntorn, Patcharin Kongwaen, Prasat Kittakoop, Somsak Ruchirawat.
Publications Date : 21 Apr 2025 - Photoinduced Cascade Reaction of Ene-Yne-Oxazoles with Trimethylsilyl Azide and N-Iodosuccinamide: Synthesis of Azidyl Spiroindenoxazolones
Author(s) : Sireethon Khotsombat, Rattana Worayuthakarn, Kittipong Chainok, Somsak Ruchirawat, Nopporn Thasana.
Publications Date : 14 Apr 2025 - Synthesis, Biological Evaluation, Molecular Docking, and In Silico ADME Predictions of Huperzine: A Derivative for the Novel Protective Application Against Neurodegenerations
Author(s) : Benjaporn Homkajorn, Thanasan Nilsu, Sumitra Suntararuks, Patchreenart Saparpakorn, Kornkanok Ingkaninan, Nanteetip Limpeanchob, Jutamaad Satayavivad, Somsak Ruchirawat, Nopporn Thasana.
Publications Date : 08 Apr 2025 - Strategic Methodologies for Efficient Synthesis of Imidazo[1,5-a]pyridine and Benzazepine Analogs via the Unique Ritter-Type Reaction
Author(s) : Gunniga Tanomsiri, Suthimon Boonmee, Nattawadee Chaisan, Jumreang Tummatorn, Charnsak Thongsornkleeb, Somsak Ruchirawat.
Publications Date : 07 Apr 2025 - In Vitro Development of Local Antiviral Formulations with Potent Virucidal Activity Against SARS-CoV-2 and Influenza Viruses
Author(s) : Juthaporn Ponphaiboon, Wantanwa Krongrawa, Sontaya Limmatvapirat, Sukannika Tubtimsri, Akanitt Jittmittraphap, Pornsawan Leaungwutiwong, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop, Chutima Limmatvapirat.
Publications Date : 27 Mar 2025 - Structurally Similar Mycotoxins Aflatoxin B1 and Sterigmatocystin Trigger Different and Distinctive High-Resolution Mutational Spectra in Mammalian Cells
Author(s) : Pennapa Thongararm, Marisa Chancharoen, Nutchapong Suwanwong, Somsak Ruchirawat, Mathuros Ruchirawat, Bogdan I Fedeles, Robert G Croy, John M Essigmann.
Publications Date : 26 Mar 2025 - All-Carbon Quaternary Center Containing Tetrahydro-5H-benzo[c]fluorenes via Highly Stereoselective Transannular Carbocation Cyclization
Author(s) : Kasam Poonswat, Sineenart Attanonchai, Paratchata Batsomboon, Chatphorn Theppitak, Kittipong Chainok, Somsak Ruchirawat, Poonsakdi Ploypradith.
Publications Date : 17 Mar 2025 - Silver-Catalyzed and Base-Mediated Double Cyclization for the Streamlined Synthesis of Benzo[4,5]imidazo[2,1-b]naphtho[2,3-d]oxazole from ortho-Alkynylarylketones
Author(s) : Kanokwan Jaithum, Jumreang Tummatorn, Chatphorn Theppitak, Kittipong Chainok, Charnsak Thongsornkleeb, Somsak Ruchirawat.
Publications Date : 13 Mar 2025 - Intramolecular Diels-Alder Reaction of Benzo-Tethered Dienyl Cinnamates: Synthesis of the Tricyclic Core of Morusalisin A
Author(s) : Poramate Songthammawat, Kasam Poonswat, Pisit Nithijarasrawee, Poonsakdi Ploypradith, Somsak Ruchirawat.
Publications Date : 08 Mar 2025 - Biological activity of prenylated pyranoflavanones from the stems of Derris reticulata
Author(s) : Sakunchai Khumsubdee, Hunsa Prawat, Wirongrong Kaweetripob, Surasak Kheawchaum, Jutatip Boonsombat, Chulabhorn Mahidol, Somsak Ruchirawat.
Publications Date : 06 Mar 2025 - Enhanced Anti-Inflammatory and Skin Barrier Repair Effects of Nanoemulsions Supplemented with Boesenbergia rotunda for Atopic Dermatitis
Author(s) : Desy Liana, Jaruwan Chatwichien, Anuchit Phanumartwiwath.
Publications Date : 24 Feb 2025 - Hypervalent Iodine(III)-Mediated Oxidative Cyclization of Exo-Cyclic Ene-Carbamate to Tetrahydroisoquinoline-Oxazol-2(3H)-one Derivatives
Author(s) : Suphaporn Limjirawatthana, Poonsakdi Ploypradith, Somsak Ruchirawat, Chatphorn Theppitak, Winai Ieawsuwan.
Publications Date : 24 Feb 2025 - Effects of organic salts of virucidal and antiviral compounds from Nelumbo nucifera and Kaempferia parviflora against SARS-CoV-2
Author(s) : Dan-Dan Yang, Nopporn Chutiwitoonchai, Feng Wang, Ping Tian, Sanya Sureram, Xiaoguang Lei, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop.
Publications Date : 21 Feb 2025 - Virucidal activity of tiliacorinine, dioscorine, racemosol, and terrein against influenza A virus (H1N1), coronavirus 229E, SARS-CoV-2, and enterovirus 71
Author(s) : Akanitt Jittmittraphap, Pornsawan Leaungwutiwong, Piyawan Meechokedee, Siriporn Chattanadee, Narin Thippornchai, Sanya Sureram, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop.
Publications Date : 19 Feb 2025 - Synthesis, biological investigation, and in silico studies of 2-aminothiazole sulfonamide derivatives as potential antioxidants
Author(s) : Apilak Worachartcheewan, Ratchanok Pingaew, Veda Prachayasittikul, Setthawut Apiraksattayakul, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul.
Publications Date : 19 Feb 2025 - Chromones from stems of Harrisonia perforata
Author(s) : Sakunchai Khumsubdee, Vilailak Prachyawarakorn, Chulabhorn Mahidol, Poonsakdi Ploypradith, Somsak Ruchirawat, Phanruethai Pailee.
Publications Date : 11 Feb 2025 - Molecular Engineering of Cordycepin Derivatives for Enhanced Biological Activity and Stability
Author(s) : Yiming Gu, Wei Yu, Xiang Li, Yingjie Fan, Yanan Liu, Jumreang Tummatorn, Siyu Jiang, Jingyue Yang.
Publications Date : 05 Feb 2025 - Regulation of adipocyte differentiation and lipid metabolism by novel synthetic chromenes exploring anti-obesity and broader therapeutic potential
Author(s) : Kewalin Inthanon, Natthawut Wong-A-Nan, Srisulak Dheeranupattana, Andres Garcia Guerra, Neal M Davies, Chatchai Kesornpun, Sasithorn Sangher, Prasat Kittakoop.
Publications Date : 03 Feb 2025 - Lanostane Triterpenes, Flavanones and Acetogenins from the Roots of Uvaria siamensis and Their Cytotoxic Activity
Author(s) : Lueacha Tabtimmai, Kiattawee Choowongkomon, Prasat Kittakoop, Ratsami Lekphrom, Florian Thierry Schevenels, Supachai Jadsadajerm, Awat Wisetsai.
Publications Date : 27 Jan 2025 - Estrogenic and anti-estrogenic assessment of the flame retardant, 2-ethylhexyl diphenyl phosphate (EHDPP), and its metabolites: Evidence from in vitro, in silico, and transcriptome studies
Author(s) : Phum Tachachartvanich, Rapeepat Sangsuwan, Sornsawan Duangta, Panida Navasumrit, Somsak Ruchirawat, Mathuros Ruchirawat.
Publications Date : 25 Jan 2025 - Synthesis, anti-proliferation, apoptosis induction in breast cancer cells, and aromatase inhibition of coumarin-triazole hybrids: In vitro and in silico studies
Author(s) : Amporn Saekee, Pichjira Sooknual, Sakdiphong Punpai, Veda Prachayasittikul, Sakchai Hongthong, Wanlaya Tanechpongtamb, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul, Ratchanok Pingaew.
Publications Date : 21 Jan 2025
2024
- Lutein derived from Xenostegia tridentata exhibits anticancer activities against A549 lung cancer cells via hyaluronidase inhibition
Author(s) : Jaruwan Chatwichien, Natthawat Semakul, Saranphong Yimklan, Nutchapong Suwanwong, Prakansi Naksing, Somsak Ruchirawat.
Publications Date : 16 Dec 2024 - Bi(OTf)3-Catalyzed Cascade Cycloaddition-Decarbonylation-N-Deoxygenative Aromatization between 2-Arylisatogens and Styrenes: Unveiling a Synthesis of 2,4-Diarylquinolines
Author(s) : Kunlayanee Punjajom, Sukit Chonradeenitchakul, Jumreang Tummatorn, Somsak Ruchirawat, Charnsak Thongsornkleeb.
Publications Date : 15 Nov 2024 - 16S rRNA methyltransferase KsgA contributes to oxidative stress and antibiotic resistance in Pseudomonas aeruginosa
Author(s) : Kamonwan Phatinuwat, Sopapan Atichartpongkul, Watthanachai Jumpathong, Skorn Mongkolsuk, Mayuree Fuangthong.
Publications Date : 03 Nov 2024 - Chemical profile and biological activities of Lysiphyllum binatum (Blanco) de Wit
Author(s) : Surasak Kheawchaum, Sanit Thongnest, Jutatip Boonsombat, Paratchata Batsomboon, Chulabhorn Mahidol, Hunsa Prawat, Somsak Ruchirawat.
Publications Date : 25 Sep 2024 - Cascade Cyclization of o-(2-Acyl-1-ethynyl)benzaldehydes with Amino Acid Derivatives: Synthesis of Indeno[2,1-c]pyran-3-ones and 1-Oxazolonylisobenzofurans via the Erlenmeyer-Plöchl Azlactone Reaction
Author(s) : Rattana Worayuthakarn, Nattanit Suddee, Chatphorn Theppitak, Kittipong Chainok, Somsak Ruchirawat, Nopporn Thasana.
Publications Date : 16 Sep 2024 - Grewiifopenes A-K, bioactive clerodane diterpenoids from Casearia grewiifolia Vent
Author(s) : Phanruethai Pailee, Paratchata Batsomboon, Wiriya Yaosanit, Theerawat Thananthaisong, Chulabhorn Mahidol, Poonsakdi Ploypradith, Nanthawan Reuk-Ngam, Panita Khlaychan, Supanna Techasakul, Somsak Ruchirawat, Vilailak Prachyawarakorn.
Publications Date : 14 Sep 2024 - Electron Donor-Acceptor Complex-Enabled Autoinductive Conversion of Acylnitromethanes to Acylnitrile Oxides in a Photochemical Machetti-De Sarlo Reaction: Synthesis of 5-Substituted 3-Acylisoxazoles
Author(s) : Piyaporn Arunkirirote, Pornteera Suwalak, Nattawadee Chaisan, Jumreang Tummatorn, Somsak Ruchirawat, Charnsak Thongsornkleeb.
Publications Date : 30 Aug 2024 - Xanthine Oxidase Inhibition by Monoterpene-Chalcone Conjugates from Kaempferia subglobosa and Molecular Docking Insights
Author(s) : Jutatip Boonsombat, Orawan Jongsomjainuk, Sanit Thongnest, Jitnapa Sirirak, Paratchata Batsomboon, Saroj Ruchisansakun, Surasak Prachya, Chulabhorn Mahidol, Somsak Ruchirawat.
Publications Date : 30 Aug 2024 - Vernonia amygdalina Leaf Extract Induces Apoptosis in HeLa Cells: A Metabolomics and Proteomics Study
Author(s) : Pawitrabhorn Samutrtai, Yodying Yingchutrakul, Kriangsak Faikhruea, Tirayut Vilaivan, Vorrapon Chaikeeratisak, Jaruwan Chatwichien, Sucheewin Krobthong, Chanat Aonbangkhen.
Publications Date : 29 Aug 2024 - Inhibition of Giardia duodenalis by isocryptolepine -triazole adducts and derivatives
Author(s) : Supaluk Popruk, Jumreang Tummatorn, Suthasinee Sreesai, Sumate Ampawong, Tipparat Thiangtrongjit, Phornpimon Tipthara, Joel Tarning, Charnsak Thongsornkleeb, Somsak Ruchirawat, Onrapak Reamtong.
Publications Date : 16 Aug 2024 - Cholinesterase Inhibitory Activity and Molecular Docking Studies of Isocryptolepine-Triazole Adducts
Author(s) : Jumreang Tummatorn, Ittipat Meewan, Nisachon Khunnawutmanotham, Nitirat Chimnoi, Nutchapong Suwanwong, Warabhorn Rodphon, Charnsak Thongsornkleeb, Jingyue Yang, Somsak Ruchirawat.
Publications Date : 31 Jul 2024 - Huperzine A Regulates the Physiological Homeostasis of Amyloid Precursor Protein Proteolysis and Tau Protein Conformation-A Computational and Experimental Investigation
Author(s) : Suwakon Wongjaikam, Chutikorn Nopparat, Parichart Boontem, Jiraporn Panmanee, Nopporn Thasana, Mayuri Shukla, Piyarat Govitrapong.
Publications Date : 26 Jul 2024 - Synthesis, in silico, in vitro evaluation of furanyl- and thiophenyl-3-phenyl-1H-indole-2-carbohydrazide derivatives as tubulin inhibitors and anticancer agents
Author(s) : Rungroj Saruengkhanphasit, Lukana Ngiwsara, Kriengsak Lirdprapamongkol, Jaruwan Chatwichien, Worawat Niwetmarin, Chatchakorn Eurtivong, Prasat Kittakoop, Jisnuson Svasti, Somsak Ruchirawat.
Publications Date : 19 Jul 2024 - Facile metabolic reprogramming distinguishes mycobacterial adaptation to hypoxia and starvation: ketosis drives starvation-induced persistence in M. bovis BCG
Author(s) : Nick K Davis, Yok Hian Chionh, Megan E McBee, Fabian Hia, Duanduan Ma, Liang Cui, Mariam Lucila Sharaf, Weiling Maggie Cai, Watthanachai Jumpathong, Stuart S Levine, Sylvie Alonso, Peter C Dedon.
Publications Date : 15 Jul 2024 - Ligand-Based Virtual Screening for Discovery of Indole Derivatives as Potent DNA Gyrase ATPase Inhibitors Active against Mycobacterium tuberculosis and Hit Validation by Biological Assays
Author(s) : Bongkochawan Pakamwong, Paptawan Thongdee, Bundit Kamsri, Naruedon Phusi, Somjintana Taveepanich, Kampanart Chayajarus, Pharit Kamsri, Auradee Punkvang, Supa Hannongbua, Jidapa Sangswan, Khomson Suttisintong, Sanya Sureram, Prasat Kittakoop, Poonpilas Hongmanee, Pitak Santanirand, Jiraporn Leanpolchareanchai, James Spencer, Adrian J Mulholland, Pornpan Pungpo.
Publications Date : 12 Jul 2024 - Enantioselective Reductive Cyclization of Alkynyl-Tethered Cyclohexadienones Catalyzed by Rhodium Complexes
Author(s) : Yi-Fan Wang, Feng Wang, Dan-Dan Yang, Prasat Kittakoop, Yun-Xuan Tan, Ping Tian.
Publications Date : 02 Jul 2024 - Albiflorenes A-L, polyoxygenated cyclohex(a/e)ne diterpene esters from Kaempferia albiflora
Author(s) : Pornpuk Booranaseensuntorn, Jutatip Boonsombat, Sanit Thongnest, Paratchata Batsomboon, Nanthawan Reuk-Ngam, Panita Khlaychan, Saroj Ruchisansakun, Prasat Kittakoop, Supanna Techasakul, Chulabhorn Mahidol, Somsak Ruchirawat.
Publications Date : 17 Jun 2024 - Discovery of procyanidin condensed tannins of (-)-epicatechin from Kratom, Mitragyna speciosa, as virucidal agents against SARS-CoV-2
Author(s) : Sanya Sureram, Nopporn Chutiwitoonchai, Tam Pooprasert, Watchara Sangsopha, Suphitcha Limjiasahapong, Narumol Jariyasopit, Yongyut Sirivatanauksorn, Sakda Khoomrung, Chulabhorn Mahidol, Somsak Ruchirawat, Prasat Kittakoop.
Publications Date : 12 Jun 2024 - Unveiling Route for the Synthesis of Tröger's Bases Through Azide Rearrangement
Author(s) : Kanokwan Jaithum, Jumreang Tummatorn, Charnsak Thongsornkleeb, Somsak Ruchirawat.
Publications Date : 10 Jun 2024 - Metal- and photocatalyst-free approach to visible-light-induced acylation of quinoxalinones
Author(s) : Worawat Niwetmarin, Naiyana Saesian, Rungroj Saruengkhanphasit, Chatchakorn Eurtivong, Nopporn Thasana, Somsak Ruchirawat.
Publications Date : 03 May 2024 - Cytotoxic stress caused by azalamellarin D (AzaD) interferes with cellular protein translation by targeting the nutrient-sensing kinase mTOR
Author(s) : Tirawit Meerod, Rapeepat Sangsuwan, Kanawut Klumthong, Bunkuea Chantrathonkul, Nadgrita Phutubtim, Piyarat Govitrapong, Somsak Ruchirawat, Poonsakdi Ploypradith, Pattarawut Sopha.
Publications Date : 26 Apr 2024 - Two Cytochrome P450 Enzymes Form the Tricyclic Nested Skeleton of Meroterpenoids by Sequential Oxidative Reactions
Author(s) : Erlan Yang, Yongpeng Yao, Hao Su, Zhaocui Sun, Shu-Shan Gao, Sanya Sureram, Prasat Kittakoop, Keqiang Fan, Yuanyuan Pan, Xudong Xu, Zhong-Hao Sun, Guoxu Ma, Gang Liu.
Publications Date : 11 Apr 2024 - Visible Light-Induced One-Pot Carbonylation of Alkyl Halides with Aryl Formates
Author(s) : Padon Chuentragool, Aurapat Ngamnithiporn, Prachnawadee Hongboon, Somsak Ruchirawat.
Publications Date : 06 Mar 2024 - Controllable Chemoselectivity Cascade Reactions for the Synthesis of Phenanthrenols via Palladium-Catalyzed-Suzuki/Heck Reaction and Michael Addition
Author(s) : Phornphan Yongpanich, Kamonlak Chatrangsan, Jumreang Tummatorn, Charnsak Thongsornkleeb, Somsak Ruchirawat.
Publications Date : 05 Mar 2024 - Diphenyl ethers from the cultured lichen mycobiont of Graphis handelii Zahlbr
Author(s) : Thi-Minh-Dinh Tran, Chanat Aonbangkhen, Thuc-Huy Duong, Thu-Hoang-Mai Nguyen, Minh-Truong-Tho Ho, Warinthorn Chavasiri, Sutthida Wongsuwan, Jaruwan Chatwichien, Thi-Phi Giao Vo, Ngoc-Hong Nguyen, Duangnapa Kiriwan, Kiattawee Choowongkomon.
Publications Date : 26 Feb 2024 - Dihydro-10H-indeno[1,2-b]benzofurans and Tetrahydroindeno[1,2-c]isochromenes via Stereoselective Intramolecular Carbocation Cascade Cyclization
Author(s) : Kassrin Tangdenpaisal, Wichita Kheakwanwong, Somsak Ruchirawat, Poonsakdi Ploypradith.
Publications Date : 12 Feb 2024 - Chemical constituents from Microstachys chamaelea (Euphorbiaceae) with cytotoxic and antioxidant properties
Author(s) : Watchara Sangsopha, Florian T Schevenels, Ratsami Lekphrom, Somsak Ruchirawat.
Publications Date : 12 Feb 2024 - Effects of barakol from Cassia siamea on neuroblastoma SH-SY5Y cell line: A potential combined therapy with doxorubicin
Author(s) : Orapin Wongsawatkul, Paiwan Buachan, Yamaratee Jaisin, Panaree Busarakumtragul, Sunan Chainakul, Ramida Watanapokasin, Veda Prachayasittikul, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul.
Publications Date : 06 Feb 2024 - Altenusin, a fungal metabolite, alleviates TGF-β1-induced EMT in renal proximal tubular cells and renal fibrosis in unilateral ureteral obstruction
Author(s) : Natechanok Thipboonchoo, Somsak Fongsupa, Sanya Sureram, Suliporn Sa-Nguansak, Chatchai Kesornpun, Prasat Kittakoop, Sunhapas Soodvilai.
Publications Date : 06 Feb 2024 - A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress
Author(s) : Bogdan I Fedeles, Rishi Bhardwaj, Yasunobu Ishikawa, Sakunchai Khumsubdee, Matteus Krappitz, Nina Gubina, Isabel Volpe, Denise C Andrade, Parisa Westergerling, Tobias Staudner, Jake Campolo, Sally S Liu, Ke Dong, Yiqiang Cai, Michael Rehman, Anna-Rachel Gallagher, Somsak Ruchirawat, Robert G Croy, John M Essigmann, Sorin V Fedeles, Stefan Somlo.
Publications Date : 19 Jan 2024 - Synthesis, Antiacetylcholinesterase Activity, and Molecular Dynamics Simulation of Aporphine-benzylpyridinium Conjugates
Author(s) : Nisachon Khunnawutmanotham, Pichjira Sooknual, Paratchata Batsomboon, Poonsakdi Ploypradith, Nitirat Chimnoi, Apinya Patigo, Patchreenart Saparpakorn, Supanna Techasakul.
Publications Date : 17 Jan 2024
2023
- Anthelmintic efficacy evaluation and mechanism of N-methylbenzo[d]oxazol-2-amine
Author(s) : Pattaneeya Prangthip, Jumreang Tummatorn, Poom Adisakwattana, Naphatsamon Uthailak, Usa Boonyuen, Phornpimon Tipthara, Joel Tarning, Pavitra Laohapaisan, Charnsak Thongsornkleeb, Somsak Ruchirawat, Onrapak Reamtong.
Publications Date : 21 Dec 2023 - Anti-Xanthine Oxidase 5'-Hydroxyhericenes A-D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-1-yl]-pyridine-4,5-diol
Author(s) : Tawatchai Thongkongkaew, Narumol Jariyasopit, Sakda Khoomrung, Siraprapa Siritutsoontorn, Sarawut Jitrapakdee, Prasat Kittakoop, Somsak Ruchirawat.
Publications Date : 11 Dec 2023 - A toluidine blue/porous organic polymer/2D MoSe2 nanocomposite as an electrochemical signaling platform for a sensitive label-free aflatoxin B1 bioassay in some crops
Author(s) : Patrawadee Yaiwong, Kamonluck Iamsawat, Sirakorn Wiratchan, Watthanachai Jumpathong, Natthawat Semakul, Suwussa Bamrungsap, Jaroon Jakmunee, Kontad Ounnunkad.
Publications Date : 09 Dec 2023 - Kaemtakols A-D, highly oxidized pimarane diterpenoids with potent anti-inflammatory activity from Kaempferia takensis
Author(s) : Orawan Jongsomjainuk, Jutatip Boonsombat, Sanit Thongnest, Hunsa Prawat, Paratchata Batsomboon, Sitthivut Charoensutthivarakul, Saroj Ruchisansakun, Kittipong Chainok, Jitnapa Sirirak, Chulabhorn Mahidol, Somsak Ruchirawat.
Publications Date : 30 Nov 2023 - Molecular Reconstruction with Stereochemical Relay: An Investigation into the Rearrangement of Spiro[4.5]decadienone to Benzoxepane
Author(s) : Satapanawat Sittihan, Shingo Harada, Tomohiro Isono, Tetsuhiro Nemoto, Somsak Ruchirawat.
Publications Date : 21 Nov 2023 - Base-Mediated and Silver-Catalyzed Divergent Synthesis of Hydroxynaphthalenamides and Phosphorylated Dihydronaphthylamides from Enone-Oxazolones
Author(s) : Rattana Worayuthakarn, Kanyanat Boontan, Kittipong Chainok, Somsak Ruchirawat, Nopporn Thasana.
Publications Date : 17 Nov 2023 - Divergent synthesis of 3,4-dihydro-2H-benzo[h]chromen-2-one and fluorenone derivatives from ortho-alkynylarylketones
Author(s) : Jantra Jantrapirom, Nitwaree Palavong, Jumreang Tummatorn, Charnsak Thongsornkleeb, Somsak Ruchirawat.
Publications Date : 30 Oct 2023 - Novel Potent Autophagy Inhibitor Ka-003 Inhibits Dengue Virus Replication
Author(s) : Jitra Limthongkul, Kornkamon Akkarasereenon, Tanpitcha Yodweerapong, Poramate Songthammawat, Pirut Tong-Ngam, Alisa Tubsuwan, Nawapol Kunkaew, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Warawuth Wannalo, Sukathida Ubol, Suparerk Borwornpinyo, Poonsakdi Ploypradith, Marisa Ponpuak.
Publications Date : 28 Oct 2023 - Phukettosides A-E, mono- and bis-iridoid glycosides, from the leaves of Morinda umbellata L
Author(s) : Wirongrong Kaweetripob, Sanit Thongnest, Jutatip Boonsombat, Paratchata Batsomboon, Abdul-Wahab Salae, Hunsa Prawat, Chulabhorn Mahidol, Somsak Ruchirawat.
Publications Date : 18 Oct 2023 - Aminochalcones Attenuate Neuronal Cell Death under Oxidative Damage via Sirtuin 1 Activity
Author(s) : Setthawut Apiraksattayakul, Ratchanok Pingaew, Ronnakorn Leechaisit, Veda Prachayasittikul, Waralee Ruankham, Napat Songtawee, Tanawut Tantimongcolwat, Somsak Ruchirawat, Virapong Prachayasittikul, Supaluk Prachayasittikul, Kamonrat Phopin.
Publications Date : 25 Sep 2023 - Microwave-assisted commercial copper-catalyzed aerobic oxidative synthesis of AChE quinazolinone inhibitors under solvent free conditions
Author(s) : Jira Jongcharoenkamol, Prakansi Naksing, Nattayaporn Nimnuan, Thishana Singh, Jaruwan Chatwichien, Prapapan Temkitthawon, Chanitsara Sriwattanawarunyoo, Vachira Choommongkol, Puttinan Meepowpan, Sutthichat Kerdphon.
Publications Date : 20 Sep 2023 - Discovery of Novel Naphthoquinone-Chalcone Hybrids as Potent FGFR1 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling
Author(s) : Ronnakorn Leechaisit, Panupong Mahalapbutr, Pornthip Boonsri, Kun Karnchanapandh, Thanyada Rungrotmongkol, Veda Prachayasittikul, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul, Ratchanok Pingaew.
Publications Date : 18 Sep 2023 - In vitro evaluation of the anti‑breast cancer properties and gene expression profiles of Thai traditional formulary medicine extracts
Author(s) : Ariya Khamwut, Pavit Klomkliew, Watthanachai Jumpathong, Pornchai Kaewsapsak, Prangwalai Chanchaem, Pavaret Sivapornnukul, Kridsana Chantanakat, Nattanan Panjaworayan T-Thienprasert, Sunchai Payungporn.
Publications Date : 18 Sep 2023 - Selective electrophilic cyclization of ortho-carbonylarylacetylenols for the synthesis of cyclopenta[a]naphthalenol and 2-phenylnaphthalen-1-ol analogs
Author(s) : Jantra Jantrapirom, Phornphan Yongpanich, Jumreang Tummatorn, Kittipong Chainok, Suwadee Jiajaroen, Charnsak Thongsornkleeb, Somsak Ruchirawat.
Publications Date : 13 Sep 2023 - UHPLC-QQQ-MS and RP-HPLC Detection of Bioactive Alizarin and Scopoletin Metabolites from Morinda citrifolia Root Extracts and Their Antitubercular, Antibacterial, and Antioxidant Activities
Author(s) : Pornpat Sam-Ang, Anuchit Phanumartwiwath, Desy Liana, Sanya Sureram, Poonpilas Hongmanee, Prasat Kittakoop.
Publications Date : 21 Aug 2023 - The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation
Author(s) : Pornsuda Chawengrum, Natthaorn Luepongpatthana, Sanit Thongnest, Jitnapa Sirirak, Jutatip Boonsombat, Kriengsak Lirdprapamongkol, Siriporn Keeratichamroen, Patcharin Kongwaen, Phreeranat Montatip, Prasat Kittakoop, Jisnuson Svasti, Somsak Ruchirawat.
Publications Date : 18 Aug 2023 - Protein Modification via Nitrile Oxide-Dehydroalanine Cycloaddition: Formation of Isoxazoline Ring on the Protein Backbone
Author(s) : Anuchit Phanumartwiwath, Chatchai Kesornpun, Daranee Chokchaichamnankit, Amnart Khongmanee, Penchatr Diskul-Na-Ayudthaya, Theetat Ruangjaroon, Chantragan Srisomsap, Prasat Kittakoop, Jisnuson Svasti, Somsak Ruchirawat.
Publications Date : 18 May 2023 - Mn(OAc)3-Mediated One-Pot Condensation-Oxidative Annulation of 2-Alkynylanilines and 1,3-Ketoesters: Synthesis of 2-Substituted Quinolines
Author(s) : Kunlayanee Punjajom, Sureeporn Ruengsangtongkul, Jumreang Tummatorn, Praneet Paiboonsombat, Somsak Ruchirawat, Charnsak Thongsornkleeb.
Publications Date : 05 May 2023 - Schomburginones A‒J, geranylated benzophenones from the leaves of Garcinia schomburgkiana and their cytotoxic and anti-inflammatory activities
Author(s) : Edwin R Sukandar, Sutin Kaennakam, Sutthida Wongsuwan, Jaruwan Chatwichien, Sucheewin Krobthong, Yodying Yingchutrakul, Thanisorn Mahatnirunkul, Fadjar Mulya, Vudhichai Parasuk, David J Harding, Preeyaporn Poldorn, Thanyada Rungrotmongkol, Santi Tip-Pyang, Chanat Aonbangkhen, Warinthorn Chavasiri.
Publications Date : 01 May 2023 - Bioisosteric Design Identifies Inhibitors of Mycobacterium tuberculosis DNA Gyrase ATPase Activity
Author(s) : Bundit Kamsri, Bongkochawan Pakamwong, Paptawan Thongdee, Naruedon Phusi, Pharit Kamsri, Auradee Punkvang, Sombat Ketrat, Patchreenart Saparpakorn, Supa Hannongbua, Jidapa Sangswan, Khomson Suttisintong, Sanya Sureram, Prasat Kittakoop, Poonpilas Hongmanee, Pitak Santanirand, Jiraporn Leanpolchareanchai, Kirsty E Goudar, James Spencer, Adrian J Mulholland, Pornpan Pungpo.
Publications Date : 19 Apr 2023 - A Mechanistically Deceiving Formation of Aryl(1-indanyl)ketones via Acid-Catalyzed Cyclization of ortho-Alkynylarylmethanols
Author(s) : Warabhorn Rodphon, Sutida Linkhum, Charnsak Thongsornkleeb, Jumreang Tummatorn, Somsak Ruchirawat.
Publications Date : 21 Mar 2023 - Two new serratene triterpenes from club moss cultivars
Author(s) : Wachirasak Thaisaeng, Wanlaya Thamnarak, Somsak Ruchirawat, Kittipong Chainok, Nopporn Thasana.
Publications Date : 13 Mar 2023 - Fabrication, Optimization, and Characterization of Antibacterial Electrospun Shellac Fibers Loaded with Kaempferia parviflora Extract
Author(s) : Wantanwa Krongrawa, Sontaya Limmatvapirat, Mont Kumpugdee Vollrath, Prasat Kittakoop, Supachai Saibua, Chutima Limmatvapirat.
Publications Date : 21 Jan 2023 - A structure-based virtual high-throughput screening, molecular docking, molecular dynamics and MM/PBSA study identified novel putative drug-like dual inhibitors of trypanosomal cruzain and rhodesain cysteine proteases
Author(s) : Chatchakorn Eurtivong, Collin Zimmer, Tanja Schirmeister, Chutikarn Butkinaree, Rungroj Saruengkhanphasit, Worawat Niwetmarin, Somsak Ruchirawat, Avninder S Bhambra.
Publications Date : 08 Jan 2023
2022
- Phlegcarines A-C, three Lycopodium alkaloids from Phlegmariurus carinatus (Desv. ex Poir.) Ching
Author(s) : Wanlaya Thamnarak, Wachirasak Thaisaeng, Paratchata Batsomboon, Chatchakorn Eurtivong, Nanthawat Wannarit, Somsak Ruchirawat, Nopporn Thasana.
Publications Date : 08 Dec 2022 - Discovery of N-methylbenzo[d]oxazol-2-amine as new anthelmintic agent through scalable protocol for the synthesis of N-alkylbenzo[d]oxazol-2-amine and N-alkylbenzo[d]thiazol-2-amine derivatives
Author(s) : Pavitra Laohapaisan, Onrapak Reamtong, Jumreang Tummatorn, Charnsak Thongsornkleeb, Urusa Thaenkham, Poom Adisakwattana, Somsak Ruchirawat.
Publications Date : 01 Dec 2022 - Functionalized Chromans from ortho-Quinone Methides and Arylallenes
Author(s) : Kornkamon Akkarasereenon, Paratchata Batsomboon, Somsak Ruchirawat, Poonsakdi Ploypradith.
Publications Date : 14 Nov 2022 - Synthesis of acetamidosulfonamide derivatives with antioxidative and QSAR studies
Author(s) : Apilak Worachartcheewan, Somchai Pisutjaroenpong, Ratchanok Pingaew, Supaluk Prachayasittikul, Suphakit Siriwong, Somsak Ruchirawat, Virapong Prachayasittikul.
Publications Date : 02 Nov 2022 - Synergistic Lewis-Brønsted Acid Catalysis in Cascade Cyclization of ortho-Alkynylaryl Cyclopropylketones for the Synthesis of 2,3-Dihydronaphtho[1,2-b]furans
Author(s) : Kanokwan Jaithum, Charnsak Thongsornkleeb, Jumreang Tummatorn, Somsak Ruchirawat.
Publications Date : 25 Oct 2022 - Acetogenins from the stems of Uvaria micrantha showing antiproliferative effects on HepG2 liver cancer cells
Author(s) : Sanit Thongnest, Jutatip Boonsombat, Siriporn Keeratichamroen, Kriengsak Lirdprapamongkol, Wirongrong Kaweetripob, Surasak Kheawchaum, Chulabhorn Mahidol, Jisnuson Svasti, Somsak Ruchirawat, Hunsa Prawat.
Publications Date : 26 Sep 2022 - Traveling Wave Ion Mobility-Derived Collision Cross Section Database for Plant Specialized Metabolites: An Application to Ventilago harmandiana Pierre
Author(s) : Narumol Jariyasopit, Suphitcha Limjiasahapong, Alongkorn Kurilung, Sitanan Sartyoungkul, Pattipong Wisanpitayakorn, Narong Nuntasaen, Chutima Kuhakarn, Vichai Reutrakul, Prasat Kittakoop, Yongyut Sirivatanauksorn, Sakda Khoomrung.
Publications Date : 26 Sep 2022 - Discovery of nitric oxide-inducing activities of synthetic LAM glycan motifs prepared by scalable rapid syntheses
Author(s) : Nutchapong Suwanwong, Jaruwan Chatwichien, Kittipong Chainok, Somsak Ruchirawat, Siwarutt Boonyarattanakalin.
Publications Date : 10 Sep 2022 - Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity
Author(s) : Paptawan Thongdee, Chayanin Hanwarinroj, Bongkochawan Pakamwong, Pharit Kamsri, Auradee Punkvang, Jiraporn Leanpolchareanchai, Sombat Ketrat, Patchreenart Saparpakorn, Supa Hannongbua, Kanchiyaphat Ariyachaokun, Khomson Suttisintong, Sanya Sureram, Prasat Kittakoop, Poonpilas Hongmanee, Pitak Santanirand, Galina V Mukamolova, Rosemary A Blood, Yuiko Takebayashi, James Spencer, Adrian J Mulholland, Pornpan Pungpo.
Publications Date : 22 Aug 2022 - Anticancer activity and QSAR study of sulfur-containing thiourea and sulfonamide derivatives
Author(s) : Ratchanok Pingaew, Veda Prachayasittikul, Apilak Worachartcheewan, Anusit Thongnum, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul.
Publications Date : 22 Aug 2022 - Siamenflavones A-C, three undescribed biflavonoids from Selaginella siamensis Hieron. and biflavonoids from spike mosses as EGFR inhibitor
Author(s) : Adebisi Adunola Demehin, Wanlaya Thamnarak, Thomanai Lamtha, Jaruwan Chatwichien, Chatchakorn Eurtivong, Kiattawee Choowongkomon, Kittipong Chainok, Somsak Ruchirawat, Nopporn Thasana.
Publications Date : 14 Aug 2022 - Novel psoralen derivatives as anti-breast cancer agents and their light-activated cytotoxicity against HER2 positive breast cancer cells
Author(s) : Chiphada Aekrungrueangkit, Sirilak Wangngae, Anyanee Kamkaew, Ruchuta Ardkhean, Sanit Thongnest, Jutatip Boonsombat, Somsak Ruchirawat, Tanatorn Khotavivattana.
Publications Date : 05 Aug 2022 - Synthesis of Naphtho[2,3-d]oxazoles via Ag(I) Acid-Mediated Oxazole-Benzannulation of ortho-Alkynylamidoarylketones
Author(s) : Warabhorn Rodphon, Kanokwan Jaithum, Sutida Linkhum, Charnsak Thongsornkleeb, Jumreang Tummatorn, Somsak Ruchirawat.
Publications Date : 05 Jul 2022
